JJH251
Broad spectrum inhibitor of serine hydrolase ABHD4
General
Type : Carbamate, Piperidine, N-hydroxyhydantoin
Chemical_Nomenclature : [7-[(4-bromophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 4-[2-(4-chlorophenyl)ethyl]piperidine-1-carboxylate
Canonical SMILES : C1CN(CCC1CCC2=CC=C(C=C2)Cl)C(=O)ON3C(=O)C4CN(CCN4C3=O)CC5=CC=C(C=C5)Br
InChI : InChI=1S\/C27H30BrClN4O4\/c28-22-7-3-21(4-8-22)17-30-15-16-32-24(18-30)25(34)33(26(32)35)37-27(36)31-13-11-20(12-14-31)2-1-19-5-9-23(29)10-6-19\/h3-10,20,24H,1-2,11-18H2
InChIKey : ROMFPQLOEVFKDY-UHFFFAOYSA-N
Other name(s) : SCHEMBL17275279 || SR-02000002580 || SR-02000002580-1
MW : 589.9
Formula : C27H30BrClN4O4
CAS_number :
PubChem : 71710937
UniChem : ROMFPQLOEVFKDY-UHFFFAOYSA-N
Target
References (1)
| Title : AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs - Parsons_2016_Nat.Chem.Biol_12_367 |
| Author(s) : Parsons WH , Kolar MJ , Kamat SS , Cognetta AB, 3rd , Hulce JJ , Saez E , Kahn BB , Saghatelian A , Cravatt BF |
| Ref : Nat Chemical Biology , 12 :367 , 2016 |
| Abstract : |
| PubMedSearch : Parsons_2016_Nat.Chem.Biol_12_367 |
| PubMedID: 27018888 |