Title : 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis - Codony_2020_J.Med.Chem_63_9237 |
Author(s) : Codony S , Pujol E , Pizarro J , Feixas F , Valverde E , Loza MI , Brea JM , Saez E , Oyarzabal J , Pineda-Lucena A , Perez B , Perez C , Rodriguez-Franco MI , Leiva R , Osuna S , Morisseau C , Hammock BD , Vazquez-Carrera M , Vazquez S |
Ref : Journal of Medicinal Chemistry , 63 :9237 , 2020 |
Abstract : |
PubMedSearch : Codony_2020_J.Med.Chem_63_9237 |
PubMedID: 32787085 |
Title : AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice - Erikci_2020_J.Biol.Chem_295_5891 |
Author(s) : Erikci Ertunc M , Kok BP , Parsons WH , Wang JG , Tan D , Donaldson CJ , Pinto AFM , Vaughan JM , Ngo N , Lum KM , Henry CL , Coppola AR , Niphakis MJ , Cravatt BF , Saez E , Saghatelian A |
Ref : Journal of Biological Chemistry , 295 :5891 , 2020 |
Abstract : |
PubMedSearch : Erikci_2020_J.Biol.Chem_295_5891 |
PubMedID: 32152231 |
Title : Discovery of small-molecule enzyme activators by activity-based protein profiling - Kok_2020_Nat.Chem.Biol_16_997 |
Author(s) : Kok BP , Ghimire S , Kim W , Chatterjee S , Johns T , Kitamura S , Eberhardt J , Ogasawara D , Xu J , Sukiasyan A , Kim SM , Godio C , Bittencourt JM , Cameron M , Galmozzi A , Forli S , Wolan DW , Cravatt BF , Boger DL , Saez E |
Ref : Nat Chemical Biology , 16 :997 , 2020 |
Abstract : |
PubMedSearch : Kok_2020_Nat.Chem.Biol_16_997 |
PubMedID: 32514184 |
Gene_locus related to this paper: human-LYPLAL1 |
Title : Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments - Galmozzi_2018_Methods.Mol.Biol_1787_115 |
Author(s) : Galmozzi A , Parker CG , Kok BP , Cravatt BF , Saez E |
Ref : Methods Mol Biol , 1787 :115 , 2018 |
Abstract : |
PubMedSearch : Galmozzi_2018_Methods.Mol.Biol_1787_115 |
PubMedID: 29736714 |
Title : AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs - Parsons_2016_Nat.Chem.Biol_12_367 |
Author(s) : Parsons WH , Kolar MJ , Kamat SS , Cognetta AB, 3rd , Hulce JJ , Saez E , Kahn BB , Saghatelian A , Cravatt BF |
Ref : Nat Chemical Biology , 12 :367 , 2016 |
Abstract : |
PubMedSearch : Parsons_2016_Nat.Chem.Biol_12_367 |
PubMedID: 27018888 |
Title : Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes - Dominguez_2014_Nat.Chem.Biol_10_113 |
Author(s) : Dominguez E , Galmozzi A , Chang JW , Hsu KL , Pawlak J , Li W , Godio C , Thomas J , Partida D , Niessen S , O'Brien PE , Russell AP , Watt MJ , Nomura DK , Cravatt BF , Saez E |
Ref : Nat Chemical Biology , 10 :113 , 2014 |
Abstract : |
PubMedSearch : Dominguez_2014_Nat.Chem.Biol_10_113 |
PubMedID: 24362705 |
Gene_locus related to this paper: human-CES3 , mouse-Ces1d |
Title : ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue - Galmozzi_2014_Cell.Rep_9_1584 |
Author(s) : Galmozzi A , Sonne SB , Altshuler-Keylin S , Hasegawa Y , Shinoda K , Luijten IH , Chang JW , Sharp LZ , Cravatt BF , Saez E , Kajimura S |
Ref : Cell Rep , 9 :1584 , 2014 |
Abstract : |
PubMedSearch : Galmozzi_2014_Cell.Rep_9_1584 |
PubMedID: 25466254 |
Title : Application of activity-based protein profiling to study enzyme function in adipocytes - Galmozzi_2014_Methods.Enzymol_538_151 |
Author(s) : Galmozzi A , Dominguez E , Cravatt BF , Saez E |
Ref : Methods Enzymol , 538 :151 , 2014 |
Abstract : |
PubMedSearch : Galmozzi_2014_Methods.Enzymol_538_151 |
PubMedID: 24529438 |