JNH
General
Type : Biphenyl, Pyrrolidine
Chemical_Nomenclature : (2S)-2-amino-1-[(2S)-2-(aminomethyl)pyrrolidin-1-yl]-3-(4-phenylphenyl)propan-1-one
Canonical SMILES : C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)C3=CC=CC=C3)N)CN
InChI : InChI=1S\/C20H25N3O\/c21-14-18-7-4-12-23(18)20(24)19(22)13-15-8-10-17(11-9-15)16-5-2-1-3-6-16\/h1-3,5-6,8-11,18-19H,4,7,12-14,21-22H2\/t18-,19-\/m0\/s1
InChIKey : MUUVLSCVDXKQQV-OALUTQOASA-N
Other name(s) : (2S)-2-amino-1-[(2S)-2-(aminomethyl)pyrrolidin-1-yl]-3-(4-phenylphenyl)propan-1-one || 2ajl || AC1NURHX || DB08024
MW : 323.44
Formula : C20H25N3O
CAS_number :
PubChem : 5459374
UniChem : MUUVLSCVDXKQQV-OALUTQOASA-N
Target
Families : JNH ligand of proteins in family
DPP4N_Peptidase_S9
Structure :
2AJL
Protein :
human-DPP4
References (1)
| Title : Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors - Qiao_2006_Bioorg.Med.Chem.Lett_16_123 |
| Author(s) : Qiao L , Baumann CA , Crysler CS , Ninan NS , Abad MC , Spurlino JC , Desjarlais RL , Kervinen J , Neeper MP , Bayoumy SS , Williams R , Deckman IC , Dasgupta M , Reed RL , Huebert ND , Tomczuk BE , Moriarty KJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :123 , 2006 |
| Abstract : |
| PubMedSearch : Qiao_2006_Bioorg.Med.Chem.Lett_16_123 |
| PubMedID: 16236500 |
| Gene_locus related to this paper: human-DPP4 |