KW-5092
General
Type : Piperidine, Imidazole
Chemical_Nomenclature : (E)-but-2-enedioic acid\;2-[1-[2-[[5-(piperidin-1-ylmethyl)furan-2-yl]methylamino]ethyl]imidazolidin-2-ylidene]propanedinitrile
Canonical SMILES : C1CCN(CC1)CC2=CC=C(O2)CNCCN3CCNC3=C(C#N)C#N.C(=CC(=O)O)C(=O)O
InChI : InChI=1S\/C19H26N6O.C4H4O4\/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24\;5-3(6)1-2-4(7)8\/h4-5,22-23H,1-3,6-11,14-15H2\;1-2H,(H,5,6)(H,7,8) || InChI=1S\/C19H26N6O.C4H4O4\/c20-12-16(13-21)19-23-7-11-25(19)10-6-22-14-17-4-5-18(26-17)15-24-8-2-1-3-9-24\;5-3(6)1-2-4(7)8\/h4-5,22-23H,1-3,6-11,14-15H2\;1-2H,(H,5,6)(H,7,8)\/b\;2-1+
InChIKey : ULJCVCIVEVXIKD-UHFFFAOYSA-N || ULJCVCIVEVXIKD-WLHGVMLRSA-N
Other name(s) : Propanedinitrile, but-2-enedioic acid, 2-[1-[2-[[5-(1-piperidylmethyl)-2-furyl]methylamino]ethyl]imidazolidin-2-ylidene]propanedinitrile
MW : 354.45
Formula : C19H26N6O
CAS_number : 135017-85-5
UniChem : ULJCVCIVEVXIKD-UHFFFAOYSA-N || ULJCVCIVEVXIKD-WLHGVMLRSA-N
Target
Families : KW-5092 ligand of proteins in family
ACHE
References (5)
| Title : Effects of KW-5092 on antroduodenal coordination and gastric emptying in guinea-pigs - Kishibayashi_1998_J.Pharm.Pharmacol_50_1045 |
| Author(s) : Kishibayashi N , Karasawa A |
| Ref : J Pharm Pharmacol , 50 :1045 , 1998 |
| PubMedID: 9811166 |
| Title : Effect of KW-5092, novel gastroprokinetic agent, on the peristalsis in the isolated guinea pig ileum - Suzuki_1997_Jpn.J.Pharmacol_74_91 |
| Author(s) : Suzuki M , Kishibayashi N , Yokoyama T , Karasawa A |
| Ref : Japanese Journal of Pharmacology , 74 :91 , 1997 |
| PubMedID: 9195302 |
| Title : Enhancement of defecation and distal colonic motor activity by KW-5092, a novel gastroprokinetic agent, in rats - Kishibayashi_1995_Arch.Int.Pharmacodyn.Ther_329_295 |
| Author(s) : Kishibayashi N , Yokoyama T , Karasawa A |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 329 :295 , 1995 |
| PubMedID: 8540768 |
| Title : Effects of KW-5092, a novel gastroprokinetic agent, on intestinal water and electrolyte transport in rats - Kishibayashi_1995_Biol.Pharm.Bull_18_1671 |
| Author(s) : Kishibayashi N , Karasawa A |
| Ref : Biol Pharm Bull , 18 :1671 , 1995 |
| PubMedID: 8787786 |
| Title : Inhibitory effects of KW-5092, a novel gastroprokinetic agent, on the activity of acetylcholinesterase in guinea pig ileum - Kishibayashi_1994_Jpn.J.Pharmacol_66_397 |
| Author(s) : Kishibayashi N , Ishii A , Karasawa A |
| Ref : Japanese Journal of Pharmacology , 66 :397 , 1994 |
| PubMedID: 7723214 |