MHETA

non-hydrolyzable substrate analog of MHET. MHET is a monomer of polyester-terephthalate

General

Type : Benzoate, Terephthalate, Carboxamide

Chemical_Nomenclature : 4-(2-hydroxyethylcarbamoyl)benzoic acid

Canonical SMILES : C1=CC(=CC=C1C(=O)NCCO)C(=O)O

InChI : InChI=1S\/C10H11NO4\/c12-6-5-11-9(13)7-1-3-8(4-2-7)10(14)15\/h1-4,12H,5-6H2,(H,11,13)(H,14,15)

InChIKey : HGTVOBHNUAVYMK-UHFFFAOYSA-N

Other name(s) : J1K  ||  4-(2-hydroxyethylcarbamoyl)benzoate  ||  MHETa


MW : 209.20

Formula : C10H11NO4

CAS_number :

PubChem : 53876467

UniChem : HGTVOBHNUAVYMK-UHFFFAOYSA-N

Target

Families : MHETA ligand of proteins in family
Tannase Polyesterase-lipase-cutinase Carb_B_Bacteria

Structure :
7W1J 7VPB 7W6C 7W6O 7W6Q 6QGA

Protein :
idesa-mheth 9zzzz-Ple629 9firm-PHL7

References (3)

Title : Structural insight and engineering of a plastic degrading hydrolase Ple629 - Li_2022_Biochem.Biophys.Res.Commun_626_100
Author(s) : Li Z , Zhao Y , Wu P , Wang H , Li Q , nGao J , Qin HM , Wei H , Bornscheuer UT , Han X , Wei R , Liu W
Ref : Biochemical & Biophysical Research Communications , 626 :100 , 2022
Abstract :
PubMedSearch : Li_2022_Biochem.Biophys.Res.Commun_626_100
PubMedID: 35981419
Gene_locus related to this paper: 9zzzz-Ple629

Title : Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase - Pfaff_2022_ACS.Catalysis_12_9790
Author(s) : Pfaff L , Gao J , Li Z , Jackering A , Weber G , Mican J , Chen Y , Dong W , Han X , Feiler CG , Ao YF , Badenhorst CPS , Bednar D , Palm GJ , Lammers M , Damborsky J , Strodel B , Liu W , Bornscheuer UT , Wei R
Ref : ACS Catal , 12 :9790 , 2022
Abstract :
PubMedSearch : Pfaff_2022_ACS.Catalysis_12_9790
PubMedID: 35966606
Gene_locus related to this paper: 9firm-PHL7

Title : Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate - Palm_2019_Nat.Commun_10_1717
Author(s) : Palm GJ , Reisky L , Bottcher D , Muller H , Michels EAP , Walczak MC , Berndt L , Weiss MS , Bornscheuer UT , Weber G
Ref : Nat Commun , 10 :1717 , 2019
Abstract :
PubMedSearch : Palm_2019_Nat.Commun_10_1717
PubMedID: 30979881
Gene_locus related to this paper: idesa-mheth