MTDZ
There is a risk of confusion with another unrelated compound (2-Methyl-5-nitroimidazole-1-ethanol) also called MTDZ which is an antibiotic and anti protozoal infection antiamebic
General
Type : Sulfur Compound, Thiadiazol, Sulfonyl
Chemical_Nomenclature : 5-(4-methoxyphenyl)sulfanyl-2,1,3-benzothiadiazole
Canonical SMILES : COC1=CC=C(C=C1)SC2=CC3=NSN=C3C=C2
InChI : InChI=1S\/C13H10N2OS2\/c1-16-9-2-4-10(5-3-9)17-11-6-7-12-13(8-11)15-18-14-12\/h2-8H,1H3
InChIKey : HWTNFYKVXJBVLZ-UHFFFAOYSA-N
Other name(s) :
MW : 274.4
Formula : C13H10N2OS2\
CAS_number :
PubChem : 158610397
UniChem : HWTNFYKVXJBVLZ-UHFFFAOYSA-N
Target
Families : MTDZ ligand of proteins in family
ACHE
Protein :
human-ACHE
References (4)
| Title : Mechanisms involved in the antidepressant-like action of orally administered 5-((4-methoxyphenyl)thio)benzo[c][1,2,5]thiadiazole (MTDZ) in male and female mice - da Costa Rodrigues_2024_Psychopharmacology.(Berl)__ |
| Author(s) : da Costa Rodrigues K , da Conceicao Oliveira M , Dos Santos BF , de Campos Domingues NL , Fronza MG , Savegnago L , Wilhelm EA , Luchese C |
| Ref : Psychopharmacology (Berl) , : , 2024 |
| Abstract : |
| PubMedSearch : da Costa Rodrigues_2024_Psychopharmacology.(Berl)__ |
| PubMedID: 39008059 |
| Title : The Antinociceptive Responses of MTDZ to Paclitaxel-Induced Peripheral Neuropathy and Acute Nociception in Mice: Behavioral, Pharmacological, and Biochemical Approaches - da Motta_2023_Pharmaceuticals.(Basel)_16_1217 |
| Author(s) : da Motta KP , Martins CC , Macedo VM , Dos Santos BF , Domingues NLC , Luchese C , Wilhelm EA |
| Ref : Pharmaceuticals (Basel) , 16 : , 2023 |
| Abstract : |
| PubMedSearch : da Motta_2023_Pharmaceuticals.(Basel)_16_1217 |
| PubMedID: 37765025 |
| Title : A new arylsulfanyl-benzo-2,1,3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity - da Costa Rodrigues_2021_Chem.Biol.Interact_351_109736 |
| Author(s) : da Costa Rodrigues K , Leivas de Oliveira R , da Silva Chaves J , Esteves da Rocha VM , Fuzinato Dos Santos B , Fronza MG , Luis de Campos Domingues N , Savegnago L , Wilhelm EA , Luchese C |
| Ref : Chemico-Biological Interactions , 351 :109736 , 2021 |
| Abstract : |
| PubMedSearch : da Costa Rodrigues_2021_Chem.Biol.Interact_351_109736 |
| PubMedID: 34740600 |
| Title : Target enzymes in oxaliplatin-induced peripheral neuropathy in Swiss mice: A new acetylcholinesterase inhibitor as therapeutic strategy - da Motta_2021_Chem.Biol.Interact__109772 |
| Author(s) : da Motta KP , Santos BF , Domingues NLC , Luchese C , Wilhelm EA |
| Ref : Chemico-Biological Interactions , :109772 , 2021 |
| Abstract : |
| PubMedSearch : da Motta_2021_Chem.Biol.Interact__109772 |
| PubMedID: 34896366 |