Malaoxon

Results from the metabolism in vivo of Malathion( oxygen replaces the sulfur atom)

General

Type : Insecticide, Organophosphate, Sulfur Compound, Organothiophosphate

Chemical_Nomenclature : diethyl 2-dimethoxyphosphorylsulfanylbutanedioate

Canonical SMILES : CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC

InChI : InChI=1S\/C10H19O7PS\/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4\/h8H,5-7H2,1-4H3

InChIKey : WSORODGWGUUOBO-UHFFFAOYSA-N

Other name(s) : diethyl((dimethoxyphosphinyl)thio)butanedioate  ||  O,O-dimethyl-S-1,2-bis(ethoxycarbonyl)ethyl phosphorothioate  ||  Malathion-o-analog


MW : 1634-78-2

Formula : C10H19O7PS

CAS_number : 314.29

PubChem : 15415

UniChem : WSORODGWGUUOBO-UHFFFAOYSA-N

Wikipedia : Malaoxon

Target

Families : Malaoxon ligand of proteins in family
ACHE

References (5)

Title : Inhibition of carboxylesterases in SH-SY5Y human and NB41A3 mouse neuroblastoma cells by organophosphorus esters - Ehrich_1998_J.Toxicol.Environ.Health_53_385
Author(s) : Ehrich M , Correll L
Ref : J Toxicol Environ Health , 53 :385 , 1998
Abstract :
PubMedSearch : Ehrich_1998_J.Toxicol.Environ.Health_53_385
PubMedID: 9515941

Title : Rat brain acetylcholinesterase activity: developmental profile and maturational sensitivity to carbamate and organophosphorus inhibitors - Mortensen_1998_Toxicology_125_13
Author(s) : Mortensen SR , Hooper MJ , Padilla S
Ref : Toxicology , 125 :13 , 1998
Abstract :
PubMedSearch : Mortensen_1998_Toxicology_125_13
PubMedID: 9585096

Title : Inhibition of various cholinesterases with the enantiomers of malaoxon - Rodriguez_1997_Bull.Environ.Contam.Toxicol_58_171
Author(s) : Rodriguez OP , Muth GW , Berkman CE , Kim K , Thompson CM
Ref : Bulletin of Environmental Contamination & Toxicology , 58 :171 , 1997
Abstract :
PubMedSearch : Rodriguez_1997_Bull.Environ.Contam.Toxicol_58_171
PubMedID: 8975790

Title : Synthesis, absolute configuration, and analysis of malathion, malaoxon, and isomalathion enantiomers [published erratum appears in Chem Res Toxicol 1994 Mar-Apr\;7(2):275] - Berkman_1993_Chem.Res.Toxicol_6_718
Author(s) : Berkman CE , Thompson CM , Perrin SR
Ref : Chemical Research in Toxicology , 6 :718 , 1993
Abstract :
PubMedSearch : Berkman_1993_Chem.Res.Toxicol_6_718
PubMedID: 8292751

Title : Interaction of acetylcholinesterase with the enantiomers of malaoxon and isomalathion - Berkman_1993_Chem.Res.Toxicol_6_724
Author(s) : Berkman CE , Quinn DA , Thompson CM
Ref : Chemical Research in Toxicology , 6 :724 , 1993
Abstract :
PubMedSearch : Berkman_1993_Chem.Res.Toxicol_6_724
PubMedID: 8292752