Myrtucommulone-B-analog-Cpd34
Myrtus communis L. is a traditional herb with anti-inflammatory and antiseptic effects<<<; sEH IC50 = 1.93 nM
General
Type : Morpholine, Xanthene, Natural_modified, Alkaloid
Chemical_Nomenclature : (9R)-6-methoxy-2,2,4,4-tetramethyl-8-[3-(morpholin-4-yl)propyloxy]-9-(propan-2-yl)-4,9-dihydro-1H-xanthene-1,3(2H)-dione
Canonical SMILES : C13=C(C(=CC(=C1)OC)OCCCN2CCOCC2)[C@H](C4=C(O3)C(C(C(C4=O)(C)C)=O)(C)C)C(C)C
InChI : InChI=1S\/C28H39NO6\/c1-17(2)21-22-19(34-12-8-9-29-10-13-33-14-11-29)15-18(32-7)16-20(22)35-25-23(21)24(30)27(3,4)26(31)28(25,5)6\/h15-17,21H,8-14H2,1-7H3\/t21-\/m1\/s1
InChIKey : FLMWPTNUQHOKEI-OAQYLSRUSA-N
Other name(s) : Compound (+)-34 || (+)-34 || (R)-9-Isopropyl-6-methoxy-2,2,4,4-tetramethyl-8-(3-morpholinopropoxy)-4,9-dihydro-1H-xanthene-1,3(2H)-dione
Target
Families : Myrtucommulone-B-analog-Cpd34 ligand of proteins in family
Epoxide_hydrolase
Protein :
human-EPHX2
References (1)
| Title : Discovery, Synthesis of Myrtucommulone B Analogs as Soluble Epoxide Hydrolase Inhibitors and Their Biological Activities - Sun_2026_J.Med.Chem__ |
| Author(s) : Sun JR , Kang SS , Wang BL , Yang XY , Zhang Y |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Sun_2026_J.Med.Chem__ |
| PubMedID: 42013369 |