N-Chloro-dimethoxy-methyl-indol-ethan-amine
IC50 AgAChE1 0.04 (0.0310.05) microM; IC50 hAChE 14 (1216) microM; S.R 350
General
Type : Indole
Chemical_Nomenclature : N-(3-Chloro-4,5-dimethoxybenzyl)-2-(1-methyl-1H-indol-3-yl)ethan-1-amine hydrochloride
Canonical SMILES : C1(=C(C(=C(C=C1)CNCCC2=C[N](C3=CC=CC=C23)C)Cl)OC)OC
InChI : InChI=1S\/C20H23ClN2O2\/c1-23-13-15(16-6-4-5-7-17(16)23)10-11-22-12-14-8-9-18(24-2)20(25-3)19(14)21\/h4-9,13,22H,10-12H2,1-3H3
InChIKey : BBHFBOZQRUEYFR-UHFFFAOYSA-N
Other name(s) : Compound 16
Target
Families : N-Chloro-dimethoxy-methyl-indol-ethan-amine ligand of proteins in family
ACHE
Protein :
anoga-ACHE1
References (1)
| Title : Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes - Rajeshwari_2025_RSC.Med.Chem__ |
| Author(s) : Rajeshwari R , Duvauchelle V , Lindgren C , Stangner K , Knutsson S , Forsgren N , Ekstrom F , Kamau L , Linusson A |
| Ref : RSC Med Chem , : , 2025 |
| Abstract : |
| PubMedSearch : Rajeshwari_2025_RSC.Med.Chem__ |
| PubMedID: 41551022 |
| Gene_locus related to this paper: aedae-ACHE1 , anoga-ACHE1 , human-ACHE , mouse-ACHE |