N-methoxybenzyl-methyl-indol-ethan-amine
IC50 AgAChE1 0.06 (0.0440.070) microM; IC50 hAChE 1.6 (1.51.7) microM; S.R 27
General
Type : Indole
Chemical_Nomenclature : N-(2-methoxybenzyl)-2-(1-methyl-1H-indol-3-yl)ethan-1-amine
Canonical SMILES : C1=CC(=C(C=C1)CNCCC2=C[N](C3=CC=CC=C23)C)OC
InChI : InChI=1S\/C19H22N2O\/c1-21-14-16(17-8-4-5-9-18(17)21)11-12-20-13-15-7-3-6-10-19(15)22-2\/h3-10,14,20H,11-13H2,1-2H3
InChIKey : HPUGWCXSVBHSJV-UHFFFAOYSA-N
Other name(s) : Compound 9
Target
Families : N-methoxybenzyl-methyl-indol-ethan-amine ligand of proteins in family
ACHE
Structure :
9SNJ
Protein :
mouse-ACHE
human-ACHE
anoga-ACHE1
References (1)
| Title : Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes - Rajeshwari_2025_RSC.Med.Chem__ |
| Author(s) : Rajeshwari R , Duvauchelle V , Lindgren C , Stangner K , Knutsson S , Forsgren N , Ekstrom F , Kamau L , Linusson A |
| Ref : RSC Med Chem , : , 2025 |
| Abstract : |
| PubMedSearch : Rajeshwari_2025_RSC.Med.Chem__ |
| PubMedID: 41551022 |
| Gene_locus related to this paper: aedae-ACHE1 , anoga-ACHE1 , human-ACHE , mouse-ACHE |