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Nitrophenyl-thiophen-morpholinyl-phenyl-pyrazoline-2l

IC50 hACHE 0.040 +/- 0.0019

General

Type : Sulfur Compound, Pyrazole, Morpholine, Thiophen

Chemical_Nomenclature : 1-(3-Nitrophenyl)-3-(thiophen-3-yl)-5-[4-(4-morpholinyl)phenyl]-2-pyrazoline

Canonical SMILES : C1(=CC=C(C=C1)N2CCOCC2)C3CC(=NN3C4=CC=CC(=C4)[N+](=O)[O-])C5=CSC=C5

InChI : InChI=1S\/C23H22N4O3S\/c28-27(29)21-3-1-2-20(14-21)26-23(15-22(24-26)18-8-13-31-16-18)17-4-6-19(7-5-17)25-9-11-30-12-10-25\/h1-8,13-14,16,23H,9-12,15H2

InChIKey : UJQTXHXVRBZVPI-UHFFFAOYSA-N

Other name(s) : Compound 2l

MW : 434.51

Formula : C23H22N4O3S

CAS_number :

PubChem :

UniChem : UJQTXHXVRBZVPI-UHFFFAOYSA-N

Target

Families : Nitrophenyl-thiophen-morpholinyl-phenyl-pyrazoline-2l ligand of proteins in family
ACHE

Protein :
human-ACHE

References (1)

Title : Design, Synthesis, and Evaluation of New Pyrazolines As Small Molecule Inhibitors of Acetylcholinesterase - Altintop_2024_ACS.Omega_9_31401
Author(s) : Altintop MD , Saglik Ozkan BN , Ozdemir A
Ref : ACS Omega , 9 :31401 , 2024
Abstract :
PubMedSearch : Altintop_2024_ACS.Omega_9_31401
PubMedID: 39072133