Paraquat

Paraquat is the trade name for N, N -dimethyl-4, 4 -bipyridinium dichloride, one of the most widely used herbicides in the world. A large majority (93%) of fatalities from paraquat poisoning are cases of intentional self-administration, ie, suicides. In third world countries, paraquat is a major suicide agent.. Not a potent inhibitor of cholinesterases

General

Type : Herbicide, Not A\/B H target

Chemical_Nomenclature : 1,1'-Dimethyl-4,4'-bipyridinium\; N,N'-dimethyl-gamma,gamma'-dipyridylium || 1,1'Dimethyl-4,4'bipyridinium dichloride

Canonical SMILES : C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)C

InChI : InChI=1S\/C12H14N2\/c1-13-7-3-11(4-8-13)12-5-9-14(2)10-6-12\/h3-10H,1-2H3\/q+2

InChIKey : INFDPOAKFNIJBF-UHFFFAOYSA-N

Other name(s) : Gramoxone,Paraquat dichloride, Methyl viologen, paraquat + linuron + metolachlor  ||  Starfire 1.5  ||  orthoparaquat


MW : 186.26

Formula : C12H14N2

CAS_number : 4685-14-7

PubChem : 15939

UniChem : INFDPOAKFNIJBF-UHFFFAOYSA-N

Wikipedia : Paraquat

Target

Families : Paraquat ligand of proteins in family
BCHE ACHE

References (6)

Title : Quantitative distributions of different cholinesterases and inhibition of acetylcholinesterase by metidathion and paraquat in alimentary canal of common carp - Lang_1997_Gen.Pharmacol_29_55
Author(s) : Lang G , Kufcsak O , Szegletes T , Nemcsok J
Ref : General Pharmacology , 29 :55 , 1997
Abstract :
PubMedSearch : Lang_1997_Gen.Pharmacol_29_55
PubMedID: 9195193

Title : Effects of paraquat on survival and total cholinesterase activity in fry of Cnesterodon decemmaculatus (Pisces, Poeciliidae) -
Author(s) : Di Marzio WD , Tortorelli MC
Ref : Bulletin of Environmental Contamination & Toxicology , 52 :274 , 1994
PubMedID: 8123989

Title : The effect of pesticides on carp (Cyprinus carpio L). Acetylcholinesterase and its biochemical characterization - Szabo_1992_Ecotoxicol.Environ.Saf_23_39
Author(s) : Szabo A , Nemcsok J , Asztalos B , Rakonczay Z , Kasa P , Hieu LH
Ref : Ecotoxicology & Environmental Safety , 23 :39 , 1992
Abstract :
PubMedSearch : Szabo_1992_Ecotoxicol.Environ.Saf_23_39
PubMedID: 1375147

Title : Safety\/risk assessment of pesticides: principles, procedures and examples - Lu_1992_Toxicol.Lett_64_783
Author(s) : Lu FC , Dourson ML
Ref : Toxicol Lett , 64-65 :783 , 1992
Abstract :
PubMedSearch : Lu_1992_Toxicol.Lett_64_783
PubMedID: 1471237

Title : Effects of paraquat on canine bronchoalveolar lavage fluid - Hampson_1989_Toxicol.Appl.Pharmacol_98_206
Author(s) : Hampson EC , Eyles DW , Pond SM
Ref : Toxicol Appl Pharmacol , 98 :206 , 1989
Abstract :
PubMedSearch : Hampson_1989_Toxicol.Appl.Pharmacol_98_206
PubMedID: 2711387

Title : Structure-activity relationship of reversible cholinesterase inhibitors including paraquat - Seto_1988_Arch.Toxicol_62_37
Author(s) : Seto Y , Shinohara T
Ref : Archives of Toxicology , 62 :37 , 1988
Abstract :
PubMedSearch : Seto_1988_Arch.Toxicol_62_37
PubMedID: 3190453