Phosphopantetheine
General
Type : Sulfur Compound
Chemical_Nomenclature : [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] dihydrogen phosphate
Canonical SMILES : CC(C)(COP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O
InChI : InChI=1S\/C11H23N2O7PS\/c1-11(2,7-20-21(17,18)19)9(15)10(16)13-4-3-8(14)12-5-6-22\/h9,15,22H,3-7H2,1-2H3,(H,12,14)(H,13,16)(H2,17,18,19)\/t9-\/m0\/s1
InChIKey : JDMUPRLRUUMCTL-VIFPVBQESA-N
Other name(s) : 4'-Phosphopantetheine || D-Pantetheine 4'-phosphate || pantetheine 4'-phosphate || SCHEMBL106050 || CHEBI:4222 || DB03912
MW : 358.35
Formula : C11H23N2O7PS
CAS_number : 2226-71-3
PubChem : 115254
UniChem : JDMUPRLRUUMCTL-VIFPVBQESA-N
Target
Families : Phosphopantetheine ligand of proteins in family
Thioesterase
Structure :
8W2D
Protein :
9burk-SulM.TTE
ratno-sast
human-OLAH
References (3)
| Title : The structure of the monobactam-producing thioesterase domain of SulM forms a unique complex with the upstream carrier protein domain - Patel_2024_J.Biol.Chem_300_107489 |
| Author(s) : Patel KD , Oliver RA , Lichstrahl MS , Li R , Townsend CA , Gulick AM |
| Ref : Journal of Biological Chemistry , 300 :107489 , 2024 |
| Abstract : |
| PubMedSearch : Patel_2024_J.Biol.Chem_300_107489 |
| PubMedID: 38908753 |
| Title : Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis - Ho_2023_Chem.Commun.(Camb)_59_8234 |
| Author(s) : Ho YTC , Kaczmarski JA , Tailhades J , Izore T , Steer DL , Schittenhelm RB , Tosin M , Jackson CJ , Cryle MJ |
| Ref : Chem Commun (Camb) , 59 :8234 , 2023 |
| Abstract : |
| PubMedSearch : Ho_2023_Chem.Commun.(Camb)_59_8234 |
| PubMedID: 37310188 |
| Title : The carboxyl-terminal region of thioesterase II participates in the interaction with fatty acid synthase. Use of electrospray ionization mass spectrometry to identify a carboxyl-terminally truncated form of the enzyme - Witkowska_1990_J.Biol.Chem_265_5662 |
| Author(s) : Witkowska HE , Green BN , Smith S |
| Ref : Journal of Biological Chemistry , 265 :5662 , 1990 |
| Abstract : |
| PubMedSearch : Witkowska_1990_J.Biol.Chem_265_5662 |
| PubMedID: 2318831 |