Pyrazole-carboxamide-derivative-CpdS1
General
Type : Pyrazole, Carboxamide, Pyrimidine, Sulfur Compound, Multitarget, Carbonic anhydrase inhibitor
Chemical_Nomenclature : N-4-fluorophenyl-3,5-diamino-4-[(1E)-4-(4,6-dimethylpyrimidin-2-ylaminosulfonyl)phenylazo]-2H-pyrazole-2-carboxamide
Canonical SMILES : C1=CC(=CC=C1[S](NC2=NC(=CC(=N2)C)C)(=O)=O)N=NC3=C([N](N=C3N)C(NC4=CC=C(C=C4)F)=O)N
InChI : InChI=1S\/C22H21FN10O3S\/c1-12-11-13(2)27-21(26-12)32-37(35,36)17-9-7-16(8-10-17)29-30-18-19(24)31-33(20(18)25)22(34)28-15-5-3-14(23)4-6-15\/h3-11H,25H2,1-2H3,(H2,24,31)(H,28,34)(H,26,27,32)
InChIKey : GWJDDYWIPZWVEH-UHFFFAOYSA-N
Other name(s) : Compound S1 || N-p-Fluorophenyl-3,5-diamino-4-[(E)-p-(4,6-dimethyl-2-pyrimidinylaminosulfonyl)phenylazo]-1-pyrazolecarboxamide
Target
References (1)
| Title : Design and Synthesis of Pyrazole Carboxamide Derivatives as Selective Cholinesterase and Carbonic Anhydrase Inhibitors: Molecular Docking and Biological Evaluation - Durgun_2023_Chem.Biodivers__e202301824 |
| Author(s) : Durgun M , Akocak S , Lolak N , Topal F , Kocyigit U M , Turkes C , Isik M , Beydemir S |
| Ref : Chem Biodivers , :e202301824 , 2023 |
| Abstract : |
| PubMedSearch : Durgun_2023_Chem.Biodivers__e202301824 |
| PubMedID: 38149720 |