SCHEMBL13298979
IC50 AChE 0.43 +/- 0.02 BChE 2.5 +/- 0.12 microM
General
Type : Pyrimidine, Morpholine
Chemical_Nomenclature : 4-[2-(3-methylphenyl)pyrimidin-4-yl]morpholine
Canonical SMILES : CC1=CC(=CC=C1)C2=NC=CC(=N2)N3CCOCC3
InChI : InChI=1S\/C15H17N3O\/c1-12-3-2-4-13(11-12)15-16-6-5-14(17-15)18-7-9-19-10-8-18\/h2-6,11H,7-10H2,1H3
InChIKey : XRECENIWOQQMGF-UHFFFAOYSA-N
Other name(s) : 4-(2-(m-Tolyl)pyrimidin-4-yl)morpholine || Compound 5h
MW : 255.31
Formula : C15H17N3O
CAS_number :
PubChem : 59356561
UniChem : XRECENIWOQQMGF-UHFFFAOYSA-N
Target
Families : SCHEMBL13298979 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Pyrimidine-morpholine hybrids as potent druggable therapeutics for Alzheimer's disease: Synthesis, biochemical and in silico analyses - Zaib_2023_Bioorg.Chem_141_106868 |
| Author(s) : Zaib S , Younas MT , Khan I , Ali HS , McAdam CJ , White JM , Jaber F , Awwad NS , Ibrahium HA |
| Ref : Bioorg Chem , 141 :106868 , 2023 |
| Abstract : |
| PubMedSearch : Zaib_2023_Bioorg.Chem_141_106868 |
| PubMedID: 37738768 |