TMR-Hy5

General

Type : HaloTag-ligand, Xanthene

Chemical_Nomenclature : [9-[2-carboxy-5-[2-[2-(5-oxidanylpentoxy)ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium

Canonical SMILES : CN(C)c1ccc2c(c1)OC3=CC(=[N+](C)C)C=CC3=C2c4cc(ccc4C(=O)O)C(=O)NCCOCCOCCCCCO

InChI : InChI=1S\/C34H41N3O7\/c1-36(2)24-9-12-27-30(21-24)44-31-22-25(37(3)4)10-13-28(31)32(27)29-20-23(8-11-26(29)34(40)41)33(39)35-14-17-43-19-18-42-16-7-5-6-15-38\/h8-13,20-22,38H,5-7,14-19H2,1-4H3,(H-,35,39,40,41)\/p+1

InChIKey : JWWZUBNFGVWRTE-UHFFFAOYSA-O

Other name(s) : IYL


MW : 604.71

Formula : C34H42N3O7

CAS_number :

PubChem : 166625059

UniChem : JWWZUBNFGVWRTE-UHFFFAOYSA-O

Target

Families : TMR-Hy5 ligand of proteins in family
Haloalkane_dehalogenase-HLD2

Structure :
7ZIZ

Protein :
rhoso-halo1

References (1)

Title : Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy - Kompa_2023_J.Am.Chem.Soc_145_3075
Author(s) : Kompa J , Bruins J , Glogger M , Wilhelm J , Frei MS , Tarnawski M , x , Este E , Heilemann M , Hiblot J , Johnsson K
Ref : Journal of the American Chemical Society , 145 :3075 , 2023
Abstract :
PubMedSearch : Kompa_2023_J.Am.Chem.Soc_145_3075
PubMedID: 36716211
Gene_locus related to this paper: rhoso-halo1