Tacrine-dehydrozingerone
Acetylcholinesterase (AChE) enzyme and myeloid differentiation 2 protein (MD2) tacrine dehydrozingerone (DHZ)
General
Type : Derivative of Tacrine, Multitarget
Chemical_Nomenclature :
Canonical SMILES : C1=CC=C2C(=C1)C=C5C(=C2NCCCC(=O)CC(SC3=CC=CC=C3)C4=CC(=C(C=C4)O)OC)CCCC5
InChI : InChI=1S\/C33H35NO3S\/c1-37-31-21-25(17-18-30(31)36)32(38-27-13-3-2-4-14-27)22-26(35)12-9-19-34-33-28-15-7-5-10-23(28)20-24-11-6-8-16-29(24)33\/h2-5,7,10,13-15,17-18,20-21,32,34,36H,6,8-9,11-12,16,19,22H2,1H3
InChIKey : VKIXKNQPBWZSLF-UHFFFAOYSA-N
Other name(s) :
Target
Families : Tacrine-dehydrozingerone ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Computational approach to suggest a new multi-target-directed ligand as a potential medication for Alzheimer's disease - Eslami_2019_J.Biomol.Struct.Dyn__1 |
| Author(s) : Eslami M , Nezafat N , Negahdaripour M , Ghasemi Y |
| Ref : J Biomol Struct Dyn , :1 , 2019 |
| Abstract : |
| PubMedSearch : Eslami_2019_J.Biomol.Struct.Dyn__1 |
| PubMedID: 30689517 |