Thienopyrimidine-methoxybenzylidene-Tetrahydroisoquinoline-Cpd5
General
Type : Isoquinoline, Pyrimidine, Hydrazinylidene
Chemical_Nomenclature : (E)-3-((3-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)-4-hydroxy-5-methoxybenzylidene)amino)-2-methylthieno[3,2-d]pyrimidin-4(3H)-one
Canonical SMILES : C15C(N=C(N(C1=O)N=CC2=CC(=C(C(=C2)OC)O)CN3CC4=C(CC3)C=CC=C4)C)CCS5
InChI : InChI=1S\/C25H28N4O3S\/c1-16-27-21-8-10-33-24(21)25(31)29(16)26-13-17-11-20(23(30)22(12-17)32-2)15-28-9-7-18-5-3-4-6-19(18)14-28\/h3-6,11-13,21,24,30H,7-10,14-15H2,1-2H3
InChIKey : KIJKEKYXUCYKMW-UHFFFAOYSA-N
Other name(s) : Compound 5
Target
Families : Thienopyrimidine-methoxybenzylidene-Tetrahydroisoquinoline-Cpd5 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Targeting cholinergic dysfunction and neuroinflammation through rationally designed Thieno[3,2-d]pyrimidine hybrids - Tokali_2026_Bioorg.Chem_175_109778 |
| Author(s) : Tokali FS , Acar OO , Demir Y , Senol H , Acar B , Cakir F , Sen A |
| Ref : Bioorg Chem , 175 :109778 , 2026 |
| Abstract : |
| PubMedSearch : Tokali_2026_Bioorg.Chem_175_109778 |
| PubMedID: 41871474 |