Toluidine-Blue
Tolonium chloride is a phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery
General
Type : Dye, Drug, Phenothiazine, Sulfur Compound
Chemical_Nomenclature : (7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium
Canonical SMILES : CC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2 || CC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2.[Cl-]
InChI : InChI=1S\/C15H15N3S\/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13\/h4-8,16H,1-3H3\/p+1 || InChI=1S\/C15H15N3S.ClH\/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13\;\/h4-8,16H,1-3H3\;1H
InChIKey : KZEUBCUXBNEMSQ-UHFFFAOYSA-O || GEDVVYWLPUPJJZ-UHFFFAOYSA-N
Other name(s) : Tolonium chloride || Toluidine Blue || Toluidine Blue O || Basic Blue 17 || Blutene chloride || Tolonium || Tolonium cation || Tolonium ion || UNII-P3Y6XJA2D1 || CHEBI:87648
MW : 305.82
Formula : C15H16ClN3S
CAS_number : 56109-24-1, 92-31-9
UniChem : KZEUBCUXBNEMSQ-UHFFFAOYSA-O, GEDVVYWLPUPJJZ-UHFFFAOYSA-N
Target
Families : Toluidine-Blue ligand of proteins in family
ACHE
BCHE
Protein :
human-ACHE
human-BCHE
References (2)
| Title : Toluidine blue O modifies hippocampal amyloid pathology in a transgenic mouse model of Alzheimer's disease - Yuksel_2018_Biochimie_146_105 |
| Author(s) : Yuksel M , Biberoglu K , Onder S , Akbulut KG , Tacal O |
| Ref : Biochimie , 146 :105 , 2018 |
| Abstract : |
| PubMedSearch : Yuksel_2018_Biochimie_146_105 |
| PubMedID: 29248542 |
| Title : Toluidine blue O is a potent inhibitor of human cholinesterases - Biberoglu_2016_Arch.Biochem.Biophys_604_57 |
| Author(s) : Biberoglu K , Tek MY , Ghasemi ST , Tacal O |
| Ref : Archives of Biochemistry & Biophysics , 604 :57 , 2016 |
| Abstract : |
| PubMedSearch : Biberoglu_2016_Arch.Biochem.Biophys_604_57 |
| PubMedID: 27296777 |