Z-Gly-Pro

Product of hydrolysis of Z-Gly-Pro-AMC (7-amido-4-methylcoumarin) a fluorogenic substrate

General

Type : Peptide, Pyrrolidine, Benzyloxycarbonyl

Chemical_Nomenclature : (2S)-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carboxylic acid

Canonical SMILES : C1CC(N(C1)C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)O

InChI : InChI=1S\/C15H18N2O5\/c18-13(17-8-4-7-12(17)14(19)20)9-16-15(21)22-10-11-5-2-1-3-6-11\/h1-3,5-6,12H,4,7-10H2,(H,16,21)(H,19,20)\/t12-\/m0\/s1

InChIKey : ZTUKZKYDJMGJDC-LBPRGKRZSA-N

Other name(s) : Z-Gly-Pro-OH  ||  N-Cbz-glycyl-L-proline  ||  Z-Glycyl-L-proline  ||  (S)-1-(2-(((Benzyloxy)carbonyl)amino)acetyl)pyrrolidine-2-carboxylic acid


MW : 306.31

Formula : C15H18N2O5

CAS_number : 1160-54-9

PubChem : 439540

UniChem : ZTUKZKYDJMGJDC-LBPRGKRZSA-N

Target

Families : Z-Gly-Pro ligand of proteins in family
S9N_PPCE_Peptidase_S9

Structure :
1E8M

Protein :
pig-ppce

References (1)

Title : Structures of prolyl oligopeptidase substrate\/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue - Fulop_2001_J.Biol.Chem_276_1262
Author(s) : Fulop V , Szeltner Z , Renner V , Polgar L
Ref : Journal of Biological Chemistry , 276 :1262 , 2001
Abstract :
PubMedSearch : Fulop_2001_J.Biol.Chem_276_1262
PubMedID: 11031266
Gene_locus related to this paper: pig-ppce