di-O-octylglycero-O-(p-nitrophenyl)-n-hexyl-phosphonate

General

Type : Analogue of substrate, Lipase inhibitor, Triacylglycerol, Organophosphate, pNP

Chemical_Nomenclature : Di-O-octyl-sn-glycero)-O-(p-nitrophenyl)-n-hexylphosphonate,

Canonical SMILES : C(C(CO[P](=O)(OC1=CC=C(C=C1)[N+](=O)[O-])CCCCCC)OCCCCCCCC)OCCCCCCCC

InChI : InChI=1S\/C31H56NO7P\/c1-4-7-10-13-15-17-24-36-27-31(37-25-18-16-14-11-8-5-2)28-38-40(35,26-19-12-9-6-3)39-30-22-20-29(21-23-30)32(33)34\/h20-23,31H,4-19,24-28H2,1-3H3

InChIKey : RKYCRBXFEAPXAP-UHFFFAOYSA-N

Other name(s) :


MW : 585.76

Formula : C31H56NO7P

CAS_number :

PubChem :

UniChem : RKYCRBXFEAPXAP-UHFFFAOYSA-N

Target

Families : di-O-octylglycero-O-(p-nitrophenyl)-n-hexyl-phosphonate ligand of proteins in family
Bacterial_lip_FamI.2 Lipase_3

Protein :
burgl-lipas rhidl-lipas

References (3)

Title : Covalent inhibition of digestive lipases by chiral phosphonates - Cavalier_2000_Acc.Chem.Res_33_579
Author(s) : Cavalier JF , Buono G , Verger R
Ref : Acc Chem Res , 33 :579 , 2000
Abstract :
PubMedSearch : Cavalier_2000_Acc.Chem.Res_33_579
PubMedID: 10995195

Title : Inhibition of human gastric and pancreatic lipases by chiral alkylphosphonates. A kinetic study with 1,2-didecanoyl-sn-glycerol monolayer - Cavalier_1999_Chem.Phys.Lipids_100_3
Author(s) : Cavalier JF , Ransac S , Verger R , Buono G
Ref : Chemistry & Physic of Lipids , 100 :3 , 1999
Abstract :
PubMedSearch : Cavalier_1999_Chem.Phys.Lipids_100_3
PubMedID: 10640192

Title : Inhibition of microbial lipases with stereoisomeric triradylglycerol analog phosphonates - Stadler_1996_Biochim.Biophys.Acta_1304_229
Author(s) : Stadler P , Zandonella G , Haalck L , Spener F , Hermetter A , Paltauf F
Ref : Biochimica & Biophysica Acta , 1304 :229 , 1996
Abstract :
PubMedSearch : Stadler_1996_Biochim.Biophys.Acta_1304_229
PubMedID: 8982269
Gene_locus related to this paper: burgl-lipas