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Inhibitor Report for: VF2-Styrylpyridine-Dye

VF2 Smiles CN(C)c1ccc(cc1)/C=C/c2cc[n+](cc2)CCCCCCCCl; InChI=1S/C22H30ClN2/c1-24(2)22-12-10-20(11-13-22)8-9-21-14-18-25(19-15-21)17-7-5-3-4-6-16-23/h8-15,18-19H,3-7,16-17H2,1-2H3/q+1 ;InChIKey WTHMXSWCQZGWBE-UHFFFAOYSA-N


General
Type Pyridine, Dye, Fluorescent Probe
Chemical_Nomenclature 4-[2-[1-(7-chloroheptyl)pyridin-1-ium-4-yl]ethenyl]-N,N-dimethylaniline
Canonical SMILES CN(C)C1=CC=C(C=C1)C=CC2=CC=[N+](C=C2)CCCCCCCCl
InChI InChI=1S/C22H30ClN2/c1-24(2)22-12-10-20(11-13-22)8-9-21-14-18-25(19-15-21)17-7-5-3-4-6-16-23/h8-15,18-19H,3-7,16-17H2,1-2H3/q+1
InChIKey WTHMXSWCQZGWBE-UHFFFAOYSA-N
Other name(s) VF2 ; J3.634.176I ; 4-[2-[4-(Dimethylamino)phenyl]ethenyl]-1-(7-chloroheptyl)pyridinium
________________________________________________________________________________________________
MW|357.9
Formula|C22H30ClN2+
CAS_number|
PubChem|132505739
UniChem|WTHMXSWCQZGWBE-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | VF2-Styrylpyridine-Dye ligand of proteins in family: Haloalkane_dehalogenase-HLD2
Stucture | 2 structures: 7OO4, 7OND
Protein | rhoso-halo1

References:
Search PubMed for references concerning: VF2-Styrylpyridine-Dye
    Title: HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye
    Miro-Vinyals C, Stein A, Fischer S, Ward TR, Deliz Liang A
    Ref: Chembiochem, 22:3398, 2021 : PubMed