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Win4510

General

Type : Quaternary compound,Benzoate

Chemical_Nomenclature : 2-(diethylamino)ethyl 4-amino-2-hexoxybenzoate

Canonical SMILES : CCCCCCOC1=C(C=CC(=C1)N)C(=O)OCCN(CC)CC

InChI : InChI=1S\/C19H32N2O3\/c1-4-7-8-9-13-23-18-15-16(20)10-11-17(18)19(22)24-14-12-21(5-2)6-3\/h10-11,15H,4-9,12-14,20H2,1-3H3

InChIKey : JWHVJDDFSZNRDE-UHFFFAOYSA-N

Other name(s) : 2-n-hexoxy,4-aminodiethylaminoethylbenzoatehydrochloride,2-(4-amino-2-hexoxy-benzoyl)sulfanylethyl-diethyl-azanium chloride,Win 4510,Win4510,2-(diethylamino)ethyl 4-amino-2-(hexyloxy)benzoate,AC1L1O6B,AC1Q67U8,2-diethylaminoethyl 4-amino-2-hexoxybenzoate

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MW : 372.93

Formula : C19H33ClN2O3

CAS_number :

PubChem : 58030

UniChem : JWHVJDDFSZNRDE-UHFFFAOYSA-N

Target

Families : Win4510 ligand of proteins in family
BCHE

References (3)

1. Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine.

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35

Author(s) : Lockridge O

Ref : Pharmacol Ther , 47 :35 , 1990

Abstract : Lockridge_1990_Pharmacol.Ther_47_35

ESTHER : Lockridge_1990_Pharmacol.Ther_47_35

PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35

PubMedID: 2195556

Gene_locus related to this paper: human-BCHE

2. Differential inhibition of plasma cholinesterase variants using the dibutyrate analogue of pancuronium bromide

Title : Differential inhibition of plasma cholinesterase variants using the dibutyrate analogue of pancuronium bromide - Whittaker_1981_Hum.Hered_31_242

Author(s) : Whittaker M , Britten JJ

Ref : Hum Hered , 31 :242 , 1981

Abstract : Whittaker_1981_Hum.Hered_31_242

ESTHER : Whittaker_1981_Hum.Hered_31_242

PubMedSearch : Whittaker_1981_Hum.Hered_31_242

PubMedID: 7287015

3. The activity of various esterase inhibitors towards atypical human serum cholinesterase

Title : The activity of various esterase inhibitors towards atypical human serum cholinesterase -

Author(s) : Kalow W , Davies R0

Ref : Biochemical Pharmacology , 1 :183 , 1958

PubMedID:

Array
(
    [id] => 90
    [inhibitor] => Win4510
    [type] => Array
        (
            [0] => Quaternary compound
            [1] => Benzoate
        )

    [other_name] => Array
        (
            [0] => 2-n-hexoxy,4-aminodiethylaminoethylbenzoatehydrochloride
            [1] => 2-(4-amino-2-hexoxy-benzoyl)sulfanylethyl-diethyl-azanium chloride
            [2] => Win 4510
            [3] => Win4510
            [4] => 2-(diethylamino)ethyl 4-amino-2-(hexyloxy)benzoate
            [5] => AC1L1O6B
            [6] => AC1Q67U8
            [7] => 2-diethylaminoethyl 4-amino-2-hexoxybenzoate
        )

    [chemical_nomenclature] => 2-(diethylamino)ethyl 4-amino-2-hexoxybenzoate
    [formula] => C19H33ClN2O3
    [cas_number] => 
    [mw] => 372.93
    [pick_me_to_call] => display_script
    [kinetic_parameter] => Win4510_WT_human-BCHE || Win4510_human-BCHE
    [paper] => Kalow_1958_Biochem.Pharmacol_1_183 || Whittaker_1981_Hum.Hered_31_242 || Lockridge_1990_Pharmacol.Ther_47_35
    [comment] => 
    [gene_locus] => 
    [kin_inhibitor] => Win4510
    [cid] => 58030
    [family] => BCHE
    [inchikey] => JWHVJDDFSZNRDE-UHFFFAOYSA-N
    [canonicalsmiles] => CCCCCCOC1=C(C=CC(=C1)N)C(=O)OCCN(CC)CC
    [inchi] => InChI=1S\/C19H32N2O3\/c1-4-7-8-9-13-23-18-15-16(20)10-11-17(18)19(22)24-14-12-21(5-2)6-3\/h10-11,15H,4-9,12-14,20H2,1-3H3
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)