mamba-fasc2

Name : Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps) Fasciculin2

Species : Dendroaspis angusticeps

Organism :

Genbank :

NCBI PID : 1351325

NCBI NID :

OMIM :

Entrezgene :

Sequence :

Protein : mamba-fasc2

Peptide : mamba-fasc2

Molecular evidence

No disease by interaction

References

Title : Synthetic peptides derived from the central loop of fasciculin: structural analysis and evaluation as inhibitors of acetylcholinesterase - Falkenstein_1997_Biochim.Biophys.Acta_1340_143
Author(s) : Falkenstein RJ , Pena C
Ref : Biochimica & Biophysica Acta , 1340 :143 , 1997
Abstract :
PubMedSearch : Falkenstein_1997_Biochim.Biophys.Acta_1340_143
PubMedID: 9217024

Title : Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom - Marchot_1997_J.Biol.Chem_272_3502
Author(s) : Marchot P , Prowse CN , Kanter J , Camp S , Ackermann EJ , Radic Z , Bougis PE , Taylor P
Ref : Journal of Biological Chemistry , 272 :3502 , 1997
Abstract :
PubMedSearch : Marchot_1997_J.Biol.Chem_272_3502
PubMedID: 9013597

Title : Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin - Radic_1997_J.Biol.Chem_272_23265
Author(s) : Radic Z , Kirchhoff PD , Quinn DM , McCammon JA , Taylor P
Ref : Journal of Biological Chemistry , 272 :23265 , 1997
Abstract :
PubMedSearch : Radic_1997_J.Biol.Chem_272_23265
PubMedID: 9287336

Title : Conformational comparison in the snake toxin family - Falkenstein_1996_Int.J.Pept.Protein.Res_47_167
Author(s) : Falkenstein RJ , Pena C , Biscoglio MJ , Bonino DJ
Ref : Int J Pept Protein Res , 47 :167 , 1996
Abstract :
PubMedSearch : Falkenstein_1996_Int.J.Pept.Protein.Res_47_167
PubMedID: 8740966

Title : Binding of the neurotoxin fasciculin 2 to the acetylcholinesterase peripheral site drastically reduces the association and dissociation rate constants for N-methylacridinium binding to the active site - Rosenberry_1996_Biochemistry_35_685
Author(s) : Rosenberry TL , Rabl CR , Neumann E
Ref : Biochemistry , 35 :685 , 1996
Abstract :
PubMedSearch : Rosenberry_1996_Biochemistry_35_685
PubMedID: 8547248

Title : Fasciculin: modification of carboxyl groups and discussion of structure-activity relationship - Cervenansky_1996_Toxicon_34_718
Author(s) : Cervenansky C , Duran R , Karlsson E
Ref : Toxicon , 34 :718 , 1996
Abstract :
PubMedSearch : Cervenansky_1996_Toxicon_34_718
PubMedID: 8817817

Title : Allosteric control of acetylcholinesterase catalysis by fasciculin - Radic_1995_J.Biol.Chem_270_20391
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 270 :20391 , 1995
Abstract :
PubMedSearch : Radic_1995_J.Biol.Chem_270_20391
PubMedID: 7657613

Title : Muscarinic toxins from the venom of Dendroaspis snakes with agonist-like actions - Jerusalinsky_1995_Toxicon_33_389
Author(s) : Jerusalinsky D , Kornisiuk E , Bernabeu R , Izquierdo I , Cervenansky C
Ref : Toxicon , 33 :389 , 1995
Abstract :
PubMedSearch : Jerusalinsky_1995_Toxicon_33_389
PubMedID: 7570625

Title : Solution structure of a green mamba toxin that activates muscarinic acetylcholine receptors, as studied by nuclear magnetic resonance and molecular modeling - Segalas_1995_Biochemistry_34_1248
Author(s) : Segalas I , Roumestand C , Zinn-Justin S , Gilquin B , Menez R , Menez A , Toma F
Ref : Biochemistry , 34 :1248 , 1995
Abstract :
PubMedSearch : Segalas_1995_Biochemistry_34_1248
PubMedID: 7827075

Title : NMR and restrained molecular dynamics study of the three-dimensional solution structure of toxin FS2, a specific blocker of the L-type calcium channel, isolated from black mamba venom - Albrand_1995_Biochemistry_34_5923
Author(s) : Albrand JP , Blackledge MJ , Pascaud F , Hollecker M , Marion D
Ref : Biochemistry , 34 :5923 , 1995
Abstract :
PubMedSearch : Albrand_1995_Biochemistry_34_5923
PubMedID: 7727450

Title : Role of arginine residues for the activity of fasciculin - Cervenansky_1995_Eur.J.Biochem_229_270
Author(s) : Cervenansky C , Engstrom A , Karlsson E
Ref : European Journal of Biochemistry , 229 :270 , 1995
Abstract :
PubMedSearch : Cervenansky_1995_Eur.J.Biochem_229_270
PubMedID: 7744040

Title : Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase - van den Born_1995_Prot.Sci_4_703
Author(s) : van den Born HK , Radic Z , Marchot P , Taylor P , Tsigelny I
Ref : Protein Science , 4 :703 , 1995
Abstract :
PubMedSearch : van den Born_1995_Prot.Sci_4_703
PubMedID: 7613468

Title : Structural bases for the specificity of cholinesterase catalysis and inhibition. - Taylor_1995_Toxicol.Lett_83_453
Author(s) : Taylor P , Radic Z , Hosea NA , Camp S , Marchot P , Berman HA
Ref : Toxicology Letters , 83 :453 , 1995
Abstract :
PubMedSearch : Taylor_1995_Toxicol.Lett_83_453
PubMedID: 8597093

Title : Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target - Harel_1995_Structure_3_1355
Author(s) : Harel M , Kleywegt GJ , Ravelli RB , Silman I , Sussman JL
Ref : Structure , 3 :1355 , 1995
Abstract :
PubMedSearch : Harel_1995_Structure_3_1355
PubMedID: 8747462
Gene_locus related to this paper: torca-ACHE

Title : Expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites - Taylor_1994_Biochem.Soc.Trans_22_740
Author(s) : Taylor P , Radic Z , Kreienkamp HJ , Maeda RK , Luo ZD , Fuentes ME , Vellom DC , Pickering NA
Ref : Biochemical Society Transactions , 22 :740 , 1994
Abstract :
PubMedSearch : Taylor_1994_Biochem.Soc.Trans_22_740
PubMedID: 7821676

Title : Fasciculin inhibition of acetylcholinesterase is prevented by chemical modification of the enzyme at a peripheral site - Duran_1994_Biochim.Biophys.Acta_1201_381
Author(s) : Duran R , Cervenansky C , Dajas F , Tipton KF
Ref : Biochimica & Biophysica Acta , 1201 :381 , 1994
Abstract :
PubMedSearch : Duran_1994_Biochim.Biophys.Acta_1201_381
PubMedID: 7803468

Title : Fasciculins, enzyme site-directed polypeptides, as motor neurone research tools - Rodriguez-Ithurralde_1994_J.Neurol.Sci_124_54
Author(s) : Rodriguez-Ithurralde D , Vincent O
Ref : Journal of the Neurological Sciences , 124 :54 , 1994
Abstract :
PubMedSearch : Rodriguez-Ithurralde_1994_J.Neurol.Sci_124_54
PubMedID: 7528787

Title : Study of structure-activity relationship of fasciculin by acetylation of amino groups - Cervenansky_1994_Biochim.Biophys.Acta_1199_1
Author(s) : Cervenansky C , Engstrom A , Karlsson E
Ref : Biochimica & Biophysica Acta , 1199 :1 , 1994
Abstract :
PubMedSearch : Cervenansky_1994_Biochim.Biophys.Acta_1199_1
PubMedID: 8280746

Title : The timing of channel opening during miniature endplate currents at the frog and mouse neuromuscular junctions: effects of fasciculin-2, other anti-cholinesterases and vesamicol - Van der Kloot_1994_Pflugers.Arch_428_114
Author(s) : Van der Kloot W , Balezina OP , Molgo J , Naves LA
Ref : Pflugers Arch , 428 :114 , 1994
Abstract :
PubMedSearch : Van der Kloot_1994_Pflugers.Arch_428_114
PubMedID: 7971167

Title : Site of fasciculin interaction with acetylcholinesterase - Radic_1994_J.Biol.Chem_269_11233
Author(s) : Radic Z , Duran R , Vellom DC , Li Y , Cervenansky C , Taylor P
Ref : Journal of Biological Chemistry , 269 :11233 , 1994
Abstract :
PubMedSearch : Radic_1994_J.Biol.Chem_269_11233
PubMedID: 8157652

Title : Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin- induced inhibition - Dajas_1993_Brain.Res_616_1
Author(s) : Dajas F , Silveira R , Costa G , Castello ME , Jerusalinsky D , Medina J , Levesque D , Greenfield SA
Ref : Brain Research , 616 :1 , 1993
Abstract :
PubMedSearch : Dajas_1993_Brain.Res_616_1
PubMedID: 7689409

Title : Purification and properties of m1-toxin, a specific antagonist of m1 muscarinic receptors - Max_1993_J.Neurosci_13_4293
Author(s) : Max SI , Liang JS , Potter LT
Ref : Journal of Neuroscience , 13 :4293 , 1993
Abstract :
PubMedSearch : Max_1993_J.Neurosci_13_4293
PubMedID: 8410188

Title : Catalepsy induced by striatal acetylcholinesterase inhibition with fasciculin in rats - Castello_1992_Pharmacol.Biochem.Behav_41_547
Author(s) : Castello ME , Bolioli B , Dajas F
Ref : Pharmacol Biochem Behav , 41 :547 , 1992
Abstract :
PubMedSearch : Castello_1992_Pharmacol.Biochem.Behav_41_547
PubMedID: 1584833

Title : Vascular effects of acetylcholinesterase inhibitors in the rabbit eye: a study with fasciculin and physostigmine - Silveira_1992_J.Ocul.Pharmacol_8_129
Author(s) : Silveira R , Stjernschantz J
Ref : J Ocul Pharmacol , 8 :129 , 1992
Abstract :
PubMedSearch : Silveira_1992_J.Ocul.Pharmacol_8_129
PubMedID: 1506754

Title : Different functional pools of acetylcholinesterase induce changes in rat locus coeruleus noradrenaline metabolism - Abo_1992_Neurosci.Lett_141_111
Author(s) : Abo V , Viera L , Dajas F
Ref : Neuroscience Letters , 141 :111 , 1992
Abstract :
PubMedSearch : Abo_1992_Neurosci.Lett_141_111
PubMedID: 1508391

Title : Biochemical and behavioral effects of intraseptal microinjection of fasciculin, an irreversible acetylcholinesterase inhibitor - Quillfeldt_1991_Braz.J.Med.Biol.Res_24_499
Author(s) : Quillfeldt J , Bolioli B , Dalmaz C , Rascovsky S , Huang CH , Dias M , Ferreira MB , Schneider F , Izquierdo I , Medina JH , Dajas F
Ref : Brazilian Journal of Medical & Biological Research , 24 :499 , 1991
Abstract :
PubMedSearch : Quillfeldt_1991_Braz.J.Med.Biol.Res_24_499
PubMedID: 1823265

Title : Comparison of kinetic parameters for acetylthiocholine, soman, ketamine and fasciculin towards acetylcholinesterase in liposomes and in solution - Puu_1990_Biochem.Pharmacol_40_2209
Author(s) : Puu G , Koch M
Ref : Biochemical Pharmacology , 40 :2209 , 1990
Abstract :
PubMedSearch : Puu_1990_Biochem.Pharmacol_40_2209
PubMedID: 2244924

Title : Bilateral injection of fasciculin into the amygdala of rats: effects on two avoidance tasks, acetylcholinesterase activity, and cholinergic muscarinic receptors - Quillfeldt_1990_Pharmacol.Biochem.Behav_37_439
Author(s) : Quillfeldt J , Raskovsky S , Dalmaz C , Dias M , Huang C , Netto CA , Schneider F , Izquierdo I , Medina JH , Silveira R
Ref : Pharmacol Biochem Behav , 37 :439 , 1990
Abstract :
PubMedSearch : Quillfeldt_1990_Pharmacol.Biochem.Behav_37_439
PubMedID: 2087485

Title : Effects of local inhibition of locus coeruleus acetylcholinesterase by fasciculin in rats - Abo_1989_Neurosci.Lett_98_253
Author(s) : Abo V , Viera L , Silveira R , Dajas F
Ref : Neuroscience Letters , 98 :253 , 1989
Abstract :
PubMedSearch : Abo_1989_Neurosci.Lett_98_253
PubMedID: 2471117

Title : Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis - le Du_1989_J.Biol.Chem_264_21401
Author(s) : le Du MH , Marchot P , Bougis PE , Fontecilla-Camps JC
Ref : Journal of Biological Chemistry , 264 :21401 , 1989
Abstract :
PubMedSearch : le Du_1989_J.Biol.Chem_264_21401
PubMedID: 2592383

Title : Neurochemical and behavioral correlates of unilateral striatal acetylcholinesterase inhibition by fasciculin in rats - Bolioli_1989_Brain.Res_504_1
Author(s) : Bolioli B , Castello ME , Jerusalinsky D , Rubinstein M , Medina J , Dajas F
Ref : Brain Research , 504 :1 , 1989
Abstract :
PubMedSearch : Bolioli_1989_Brain.Res_504_1
PubMedID: 2598003

Title : Rat striatal acetylcholinesterase inhibition by fasciculin (a polypeptide from green mamba snake venom) - Dajas_1987_Neurosci.Lett_77_87
Author(s) : Dajas F , Bolioli B , Castello ME , Silveira R
Ref : Neuroscience Letters , 77 :87 , 1987
Abstract :
PubMedSearch : Dajas_1987_Neurosci.Lett_77_87
PubMedID: 3601220

Title : Fasciculin II, a protein inhibitor of acetylcholinesterase, tested on central synapses of Aplysia - Fossier_1986_Cell.Mol.Neurobiol_6_221
Author(s) : Fossier P , Baux G , Tauc L
Ref : Cellular Molecular Neurobiology , 6 :221 , 1986
Abstract :
PubMedSearch : Fossier_1986_Cell.Mol.Neurobiol_6_221
PubMedID: 3731216

Title : Anticholinesterase toxins -
Author(s) : Karlsson E , Mbugua PM , Rodriguez-Ithurralde D
Ref : Pharmacol Ther , 30 :259 , 1985
PubMedID: 3842891

Title : Effects of fasciculin 2, an anticholinesterase polypeptide from green mamba venom, on neuromuscular transmission in mouse diaphragm preparations - Anderson_1985_Neurosci.Lett_54_123
Author(s) : Anderson AJ , Harvey AL , Mbugua PM
Ref : Neuroscience Letters , 54 :123 , 1985
Abstract :
PubMedSearch : Anderson_1985_Neurosci.Lett_54_123
PubMedID: 2986055