Fasciculin2
Peptide of 61 residues isolated from Dendroaspis angusticeps (green mamba) venom. Potent inhibitor of some vertebrates AChE. More info mamba-fasc2 P0C1Z0 3SE2_DENAN dans uniprot
General
Type : Fasciculin2 variant, Natural_modified, Natural, Peptide, Sulfur Compound
Chemical_Nomenclature : TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY
Canonical SMILES : CCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CS)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CS)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC2=CN=CN2)C(=O)N3CCCC3C(=O)N4CCCC4C(=O)NC(CCCCN)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CS)C(=O)NCC(=O)NC(CS)C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CS)C(=O)NC(CS)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)N7CCCC7C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)NC(CC8=CC=C(C=C8)O)C(=O)O)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC(=O)C(CC9=CN=CN9)NC(=O)C(CO)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CS)NC(=O)C(CCSC)NC(=O)C(C(C)O)N
InChI : InChI=1S\/C276H446N88O90S10\/c1-22-131(12)210(354-216(398)132(13)310-221(403)152(46-32-78-299-273(288)289)320-246(428)178(114-368)344-262(444)213(136(17)373)358-265(447)215(138(19)375)359-264(446)214(137(18)374)356-244(426)165(95-142-104-296-124-308-142)330-247(429)176(112-366)342-235(417)164(93-140-57-63-145(377)64-58-140)329-249(431)182(118-457)349-230(412)158(71-87-463-20)325-257(439)207(285)133(14)370)260(442)337-162(91-128(6)7)243(425)355-211(134(15)371)261(443)338-169(100-196(284)382)239(421)346-181(117-456)220(402)306-107-198(384)312-156(67-69-202(388)389)229(411)331-168(99-195(283)381)238(420)343-177(113-367)248(430)350-184(120-459)250(432)328-163(92-139-55-61-144(376)62-56-139)234(416)319-153(47-33-79-300-274(290)291)223(405)316-148(41-23-27-73-277)226(408)341-175(111-365)245(427)321-154(48-34-80-301-275(292)293)224(406)317-155(49-35-81-302-276(294)295)225(407)339-173(96-143-105-297-125-309-143)266(448)363-85-39-53-191(363)270(452)362-84-38-52-190(362)255(437)324-150(43-25-29-75-279)222(404)323-159(72-88-464-21)232(414)353-209(130(10)11)259(441)336-160(89-126(2)3)218(400)304-106-197(383)311-147(45-31-77-298-272(286)287)217(399)303-108-200(386)314-180(116-455)219(401)305-109-201(387)315-187(123-462)268(450)364-86-40-54-192(364)269(451)361-83-36-50-188(361)254(436)307-110-199(385)313-170(101-204(392)393)240(422)334-171(102-205(394)395)242(424)332-166(97-193(281)379)236(418)327-161(90-127(4)5)233(415)322-157(68-70-203(390)391)231(413)352-208(129(8)9)258(440)326-151(44-26-30-76-280)228(410)348-185(121-460)252(434)351-186(122-461)253(435)357-212(135(16)372)263(445)345-179(115-369)267(449)360-82-37-51-189(360)256(438)335-172(103-206(396)397)241(423)318-149(42-24-28-74-278)227(409)347-183(119-458)251(433)333-167(98-194(282)380)237(419)340-174(271(453)454)94-141-59-65-146(378)66-60-141\/h55-66,104-105,124-138,147-192,207-215,365-378,455-462H,22-54,67-103,106-123,277-280,285H2,1-21H3,(H2,281,379)(H2,282,380)(H2,283,381)(H2,284,382)(H,296,308)(H,297,309)(H,303,399)(H,304,400)(H,305,401)(H,306,402)(H,307,436)(H,310,403)(H,311,383)(H,312,384)(H,313,385)(H,314,386)(H,315,387)(H,316,405)(H,317,406)(H,318,423)(H,319,416)(H,320,428)(H,321,427)(H,322,415)(H,323,404)(H,324,437)(H,325,439)(H,326,440)(H,327,418)(H,328,432)(H,329,431)(H,330,429)(H,331,411)(H,332,424)(H,333,433)(H,334,422)(H,335,438)(H,336,441)(H,337,442)(H,338,443)(H,339,407)(H,340,419)(H,341,408)(H,342,417)(H,343,420)(H,344,444)(H,345,445)(H,346,421)(H,347,409)(H,348,410)(H,349,412)(H,350,430)(H,351,434)(H,352,413)(H,353,414)(H,354,398)(H,355,425)(H,356,426)(H,357,435)(H,358,447)(H,359,446)(H,388,389)(H,390,391)(H,392,393)(H,394,395)(H,396,397)(H,453,454)(H4,286,287,298)(H4,288,289,299)(H4,290,291,300)(H4,292,293,301)(H4,294,295,302)\/t131-,132-,133+,134+,135+,136+,137+,138+,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,187-,188-,189-,190-,191-,192-,207-,208-,209-,210-,211-,212-,213-,214-,215-\/m0\/s1
InChIKey : MJJAZTXUQMIMKK-VYTSXJHUSA-N
Other name(s) : Toxin F7 || Eastern green mamba venom toxin F(7) || Toxin F(sub 7) (Dendroaspis angusticeps reduced) || Toxin F(sub VII) (Dendroaspis angusticeps reduced)
MW : 7 kD || 6758
Formula : C276H446N88O90S10
CAS_number : 50863-84-8
PubChem : 123131949
UniChem : MJJAZTXUQMIMKK-VYTSXJHUSA-N
References (49)
| Title : Structures of human acetylcholinesterase in complex with pharmacologically important ligands - Cheung_2012_J.Med.Chem_55_10282 |
| Author(s) : Cheung J , Rudolph MJ , Burshteyn F , Cassidy MS , Gary EN , Love J , Franklin MC , Height JJ |
| Ref : Journal of Medicinal Chemistry , 55 :10282 , 2012 |
| Abstract : |
| PubMedSearch : Cheung_2012_J.Med.Chem_55_10282 |
| PubMedID: 23035744 |
| Gene_locus related to this paper: human-ACHE |
| Title : Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation - Carletti_2010_J.Med.Chem_53_4002 |
| Author(s) : Carletti E , Colletier JP , Dupeux F , Trovaslet M , Masson P , Nachon F |
| Ref : Journal of Medicinal Chemistry , 53 :4002 , 2010 |
| Abstract : |
| PubMedSearch : Carletti_2010_J.Med.Chem_53_4002 |
| PubMedID: 20408548 |
| Gene_locus related to this paper: human-ACHE |
| Title : Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II - Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| Author(s) : Kryger G , Harel M , Giles K , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : Acta Crystallographica D Biol Crystallogr , 56 :1385 , 2000 |
| Abstract : |
| PubMedSearch : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| PubMedID: 11053835 |
| Gene_locus related to this paper: human-ACHE |
| Title : A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate - Rosenberry_1999_Chem.Biol.Interact_119-120_85 |
| Author(s) : Rosenberry TL , Mallender WD , Thomas PJ , Szegletes T |
| Ref : Chemico-Biological Interactions , 119-120 :85 , 1999 |
| Abstract : |
| PubMedSearch : Rosenberry_1999_Chem.Biol.Interact_119-120_85 |
| PubMedID: 10421442 |
| Title : 125I-labeled fasciculin 2: a new tool for quantitation of acetylcholinesterase densities at synaptic sites by EM-autoradiography - Anglister_1998_J.Neurosci.Methods_81_63 |
| Author(s) : Anglister L , Eichler J , Szabo M , Haesaert B , Salpeter MM |
| Ref : Journal of Neuroscience Methods , 81 :63 , 1998 |
| Abstract : |
| PubMedSearch : Anglister_1998_J.Neurosci.Methods_81_63 |
| PubMedID: 9696311 |
| Title : Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin - Radic_1997_J.Biol.Chem_272_23265 |
| Author(s) : Radic Z , Kirchhoff PD , Quinn DM , McCammon JA , Taylor P |
| Ref : Journal of Biological Chemistry , 272 :23265 , 1997 |
| Abstract : |
| PubMedSearch : Radic_1997_J.Biol.Chem_272_23265 |
| PubMedID: 9287336 |
| Title : Acetylcholinesterases from Elapidae snake venoms: biochemical, immunological and enzymatic characterization - Frobert_1997_Biochim.Biophys.Acta_1339_253 |
| Author(s) : Frobert Y , Creminon C , Cousin X , Remy MH , Chatel JM , Bon S , Bon C , Grassi J |
| Ref : Biochimica & Biophysica Acta , 1339 :253 , 1997 |
| Abstract : |
| PubMedSearch : Frobert_1997_Biochim.Biophys.Acta_1339_253 |
| PubMedID: 9187246 |
| Title : Synthetic peptides derived from the central loop of fasciculin: structural analysis and evaluation as inhibitors of acetylcholinesterase - Falkenstein_1997_Biochim.Biophys.Acta_1340_143 |
| Author(s) : Falkenstein RJ , Pena C |
| Ref : Biochimica & Biophysica Acta , 1340 :143 , 1997 |
| Abstract : |
| PubMedSearch : Falkenstein_1997_Biochim.Biophys.Acta_1340_143 |
| PubMedID: 9217024 |
| Title : Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom - Marchot_1997_J.Biol.Chem_272_3502 |
| Author(s) : Marchot P , Prowse CN , Kanter J , Camp S , Ackermann EJ , Radic Z , Bougis PE , Taylor P |
| Ref : Journal of Biological Chemistry , 272 :3502 , 1997 |
| Abstract : |
| PubMedSearch : Marchot_1997_J.Biol.Chem_272_3502 |
| PubMedID: 9013597 |
| Title : Asp7O in the peripheral anionic site of human butyrylcholinesterase - Masson_1996_Eur.J.Biochem_235_36 |
| Author(s) : Masson P , Froment MT , Bartels CF , Lockridge O |
| Ref : European Journal of Biochemistry , 235 :36 , 1996 |
| Abstract : |
| PubMedSearch : Masson_1996_Eur.J.Biochem_235_36 |
| PubMedID: 8631355 |
| Title : Conformational comparison in the snake toxin family - Falkenstein_1996_Int.J.Pept.Protein.Res_47_167 |
| Author(s) : Falkenstein RJ , Pena C , Biscoglio MJ , Bonino DJ |
| Ref : Int J Pept Protein Res , 47 :167 , 1996 |
| Abstract : |
| PubMedSearch : Falkenstein_1996_Int.J.Pept.Protein.Res_47_167 |
| PubMedID: 8740966 |
| Title : Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin - Marchot_1996_Prot.Sci_5_672 |
| Author(s) : Marchot P , Ravelli RB , Raves ML , Bourne Y , Vellom DC , Kanter J , Camp S , Sussman JL , Taylor P |
| Ref : Protein Science , 5 :672 , 1996 |
| Abstract : |
| PubMedSearch : Marchot_1996_Prot.Sci_5_672 |
| PubMedID: 8845756 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Binding of the neurotoxin fasciculin 2 to the acetylcholinesterase peripheral site drastically reduces the association and dissociation rate constants for N-methylacridinium binding to the active site - Rosenberry_1996_Biochemistry_35_685 |
| Author(s) : Rosenberry TL , Rabl CR , Neumann E |
| Ref : Biochemistry , 35 :685 , 1996 |
| Abstract : |
| PubMedSearch : Rosenberry_1996_Biochemistry_35_685 |
| PubMedID: 8547248 |
| Title : Fasciculin: modification of carboxyl groups and discussion of structure-activity relationship - Cervenansky_1996_Toxicon_34_718 |
| Author(s) : Cervenansky C , Duran R , Karlsson E |
| Ref : Toxicon , 34 :718 , 1996 |
| Abstract : |
| PubMedSearch : Cervenansky_1996_Toxicon_34_718 |
| PubMedID: 8817817 |
| Title : Effect of fasciculin on hydrolysis of neutral and choline esters by butyrylcholinesterase, cobra venom and chicken acetylcholinesterases - Duran_1996_Toxicon_34_959 |
| Author(s) : Duran R , Cervenansky C , Karlsson E |
| Ref : Toxicon , 34 :959 , 1996 |
| Abstract : |
| PubMedSearch : Duran_1996_Toxicon_34_959 |
| PubMedID: 8875783 |
| Title : Cloning and expression of acetylcholinesterase from Bungarus fasciatus venom. A new type of cooh-terminal domain\; involvement of a positively charged residue in the peripheral site - Cousin_1996_J.Biol.Chem_271_15099 |
| Author(s) : Cousin X , Bon S , Duval N , Massoulie J , Bon C |
| Ref : Journal of Biological Chemistry , 271 :15099 , 1996 |
| Abstract : |
| PubMedSearch : Cousin_1996_J.Biol.Chem_271_15099 |
| PubMedID: 8662867 |
| Gene_locus related to this paper: bunfa-ACHE |
| Title : Characterization of monoclonal antibodies that strongly inhibit Electrophorus electricus acetylcholinesterase - Remy_1995_Eur.J.Biochem_231_651 |
| Author(s) : Remy MH , Frobert Y , Grassi J |
| Ref : European Journal of Biochemistry , 231 :651 , 1995 |
| Abstract : |
| PubMedSearch : Remy_1995_Eur.J.Biochem_231_651 |
| PubMedID: 7649165 |
| Title : Muscarinic toxins from the venom of Dendroaspis snakes with agonist-like actions - Jerusalinsky_1995_Toxicon_33_389 |
| Author(s) : Jerusalinsky D , Kornisiuk E , Bernabeu R , Izquierdo I , Cervenansky C |
| Ref : Toxicon , 33 :389 , 1995 |
| Abstract : |
| PubMedSearch : Jerusalinsky_1995_Toxicon_33_389 |
| PubMedID: 7570625 |
| Title : Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target - Harel_1995_Structure_3_1355 |
| Author(s) : Harel M , Kleywegt GJ , Ravelli RB , Silman I , Sussman JL |
| Ref : Structure , 3 :1355 , 1995 |
| Abstract : |
| PubMedSearch : Harel_1995_Structure_3_1355 |
| PubMedID: 8747462 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Allosteric control of acetylcholinesterase catalysis by fasciculin - Radic_1995_J.Biol.Chem_270_20391 |
| Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P |
| Ref : Journal of Biological Chemistry , 270 :20391 , 1995 |
| Abstract : |
| PubMedSearch : Radic_1995_J.Biol.Chem_270_20391 |
| PubMedID: 7657613 |
| Title : Solution structure of a green mamba toxin that activates muscarinic acetylcholine receptors, as studied by nuclear magnetic resonance and molecular modeling - Segalas_1995_Biochemistry_34_1248 |
| Author(s) : Segalas I , Roumestand C , Zinn-Justin S , Gilquin B , Menez R , Menez A , Toma F |
| Ref : Biochemistry , 34 :1248 , 1995 |
| Abstract : |
| PubMedSearch : Segalas_1995_Biochemistry_34_1248 |
| PubMedID: 7827075 |
| Title : NMR and restrained molecular dynamics study of the three-dimensional solution structure of toxin FS2, a specific blocker of the L-type calcium channel, isolated from black mamba venom - Albrand_1995_Biochemistry_34_5923 |
| Author(s) : Albrand JP , Blackledge MJ , Pascaud F , Hollecker M , Marion D |
| Ref : Biochemistry , 34 :5923 , 1995 |
| Abstract : |
| PubMedSearch : Albrand_1995_Biochemistry_34_5923 |
| PubMedID: 7727450 |
| Title : Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex - Bourne_1995_Cell_83_503 |
| Author(s) : Bourne Y , Taylor P , Marchot P |
| Ref : Cell , 83 :503 , 1995 |
| Abstract : |
| PubMedSearch : Bourne_1995_Cell_83_503 |
| PubMedID: 8521480 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Role of arginine residues for the activity of fasciculin - Cervenansky_1995_Eur.J.Biochem_229_270 |
| Author(s) : Cervenansky C , Engstrom A , Karlsson E |
| Ref : European Journal of Biochemistry , 229 :270 , 1995 |
| Abstract : |
| PubMedSearch : Cervenansky_1995_Eur.J.Biochem_229_270 |
| PubMedID: 7744040 |
| Title : Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase - van den Born_1995_Prot.Sci_4_703 |
| Author(s) : van den Born HK , Radic Z , Marchot P , Taylor P , Tsigelny I |
| Ref : Protein Science , 4 :703 , 1995 |
| Abstract : |
| PubMedSearch : van den Born_1995_Prot.Sci_4_703 |
| PubMedID: 7613468 |
| Title : Structural bases for the specificity of cholinesterase catalysis and inhibition. - Taylor_1995_Toxicol.Lett_83_453 |
| Author(s) : Taylor P , Radic Z , Hosea NA , Camp S , Marchot P , Berman HA |
| Ref : Toxicology Letters , 83 :453 , 1995 |
| Abstract : |
| PubMedSearch : Taylor_1995_Toxicol.Lett_83_453 |
| PubMedID: 8597093 |
| Title : Fasciculin 2 binds to the peripheral site on acetylcholinesterase and inhibits substrate hydrolysis by slowing a step involving proton transfer during enzyme acylation - Eastman_1995_J.Biol.Chem_270_19694 |
| Author(s) : Eastman J , Wilson EJ , Cervenansky C , Rosenberry TL |
| Ref : Journal of Biological Chemistry , 270 :19694 , 1995 |
| Abstract : |
| PubMedSearch : Eastman_1995_J.Biol.Chem_270_19694 |
| PubMedID: 7649979 |
| Title : Site of fasciculin interaction with acetylcholinesterase - Radic_1994_J.Biol.Chem_269_11233 |
| Author(s) : Radic Z , Duran R , Vellom DC , Li Y , Cervenansky C , Taylor P |
| Ref : Journal of Biological Chemistry , 269 :11233 , 1994 |
| Abstract : |
| PubMedSearch : Radic_1994_J.Biol.Chem_269_11233 |
| PubMedID: 8157652 |
| Title : Expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites - Taylor_1994_Biochem.Soc.Trans_22_740 |
| Author(s) : Taylor P , Radic Z , Kreienkamp HJ , Maeda RK , Luo ZD , Fuentes ME , Vellom DC , Pickering NA |
| Ref : Biochemical Society Transactions , 22 :740 , 1994 |
| Abstract : |
| PubMedSearch : Taylor_1994_Biochem.Soc.Trans_22_740 |
| PubMedID: 7821676 |
| Title : Fasciculin inhibition of acetylcholinesterase is prevented by chemical modification of the enzyme at a peripheral site - Duran_1994_Biochim.Biophys.Acta_1201_381 |
| Author(s) : Duran R , Cervenansky C , Dajas F , Tipton KF |
| Ref : Biochimica & Biophysica Acta , 1201 :381 , 1994 |
| Abstract : |
| PubMedSearch : Duran_1994_Biochim.Biophys.Acta_1201_381 |
| PubMedID: 7803468 |
| Title : Fasciculins, enzyme site-directed polypeptides, as motor neurone research tools - Rodriguez-Ithurralde_1994_J.Neurol.Sci_124_54 |
| Author(s) : Rodriguez-Ithurralde D , Vincent O |
| Ref : Journal of the Neurological Sciences , 124 :54 , 1994 |
| Abstract : |
| PubMedSearch : Rodriguez-Ithurralde_1994_J.Neurol.Sci_124_54 |
| PubMedID: 7528787 |
| Title : The timing of channel opening during miniature endplate currents at the frog and mouse neuromuscular junctions: effects of fasciculin-2, other anti-cholinesterases and vesamicol - Van der Kloot_1994_Pflugers.Arch_428_114 |
| Author(s) : Van der Kloot W , Balezina OP , Molgo J , Naves LA |
| Ref : Pflugers Arch , 428 :114 , 1994 |
| Abstract : |
| PubMedSearch : Van der Kloot_1994_Pflugers.Arch_428_114 |
| PubMedID: 7971167 |
| Title : Study of structure-activity relationship of fasciculin by acetylation of amino groups - Cervenansky_1994_Biochim.Biophys.Acta_1199_1 |
| Author(s) : Cervenansky C , Engstrom A , Karlsson E |
| Ref : Biochimica & Biophysica Acta , 1199 :1 , 1994 |
| Abstract : |
| PubMedSearch : Cervenansky_1994_Biochim.Biophys.Acta_1199_1 |
| PubMedID: 8280746 |
| Title : Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin- induced inhibition - Dajas_1993_Brain.Res_616_1 |
| Author(s) : Dajas F , Silveira R , Costa G , Castello ME , Jerusalinsky D , Medina J , Levesque D , Greenfield SA |
| Ref : Brain Research , 616 :1 , 1993 |
| Abstract : |
| PubMedSearch : Dajas_1993_Brain.Res_616_1 |
| PubMedID: 7689409 |
| Title : Purification and properties of m1-toxin, a specific antagonist of m1 muscarinic receptors - Max_1993_J.Neurosci_13_4293 |
| Author(s) : Max SI , Liang JS , Potter LT |
| Ref : Journal of Neuroscience , 13 :4293 , 1993 |
| Abstract : |
| PubMedSearch : Max_1993_J.Neurosci_13_4293 |
| PubMedID: 8410188 |
| Title : Different functional pools of acetylcholinesterase induce changes in rat locus coeruleus noradrenaline metabolism - Abo_1992_Neurosci.Lett_141_111 |
| Author(s) : Abo V , Viera L , Dajas F |
| Ref : Neuroscience Letters , 141 :111 , 1992 |
| Abstract : |
| PubMedSearch : Abo_1992_Neurosci.Lett_141_111 |
| PubMedID: 1508391 |
| Title : Catalepsy induced by striatal acetylcholinesterase inhibition with fasciculin in rats - Castello_1992_Pharmacol.Biochem.Behav_41_547 |
| Author(s) : Castello ME , Bolioli B , Dajas F |
| Ref : Pharmacol Biochem Behav , 41 :547 , 1992 |
| Abstract : |
| PubMedSearch : Castello_1992_Pharmacol.Biochem.Behav_41_547 |
| PubMedID: 1584833 |
| Title : Vascular effects of acetylcholinesterase inhibitors in the rabbit eye: a study with fasciculin and physostigmine - Silveira_1992_J.Ocul.Pharmacol_8_129 |
| Author(s) : Silveira R , Stjernschantz J |
| Ref : J Ocul Pharmacol , 8 :129 , 1992 |
| Abstract : |
| PubMedSearch : Silveira_1992_J.Ocul.Pharmacol_8_129 |
| PubMedID: 1506754 |
| Title : Biochemical and behavioral effects of intraseptal microinjection of fasciculin, an irreversible acetylcholinesterase inhibitor - Quillfeldt_1991_Braz.J.Med.Biol.Res_24_499 |
| Author(s) : Quillfeldt J , Bolioli B , Dalmaz C , Rascovsky S , Huang CH , Dias M , Ferreira MB , Schneider F , Izquierdo I , Medina JH , Dajas F |
| Ref : Brazilian Journal of Medical & Biological Research , 24 :499 , 1991 |
| Abstract : |
| PubMedSearch : Quillfeldt_1991_Braz.J.Med.Biol.Res_24_499 |
| PubMedID: 1823265 |
| Title : Comparison of kinetic parameters for acetylthiocholine, soman, ketamine and fasciculin towards acetylcholinesterase in liposomes and in solution - Puu_1990_Biochem.Pharmacol_40_2209 |
| Author(s) : Puu G , Koch M |
| Ref : Biochemical Pharmacology , 40 :2209 , 1990 |
| Abstract : |
| PubMedSearch : Puu_1990_Biochem.Pharmacol_40_2209 |
| PubMedID: 2244924 |
| Title : Bilateral injection of fasciculin into the amygdala of rats: effects on two avoidance tasks, acetylcholinesterase activity, and cholinergic muscarinic receptors - Quillfeldt_1990_Pharmacol.Biochem.Behav_37_439 |
| Author(s) : Quillfeldt J , Raskovsky S , Dalmaz C , Dias M , Huang C , Netto CA , Schneider F , Izquierdo I , Medina JH , Silveira R |
| Ref : Pharmacol Biochem Behav , 37 :439 , 1990 |
| Abstract : |
| PubMedSearch : Quillfeldt_1990_Pharmacol.Biochem.Behav_37_439 |
| PubMedID: 2087485 |
| Title : Effects of local inhibition of locus coeruleus acetylcholinesterase by fasciculin in rats - Abo_1989_Neurosci.Lett_98_253 |
| Author(s) : Abo V , Viera L , Silveira R , Dajas F |
| Ref : Neuroscience Letters , 98 :253 , 1989 |
| Abstract : |
| PubMedSearch : Abo_1989_Neurosci.Lett_98_253 |
| PubMedID: 2471117 |
| Title : Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis - le Du_1989_J.Biol.Chem_264_21401 |
| Author(s) : le Du MH , Marchot P , Bougis PE , Fontecilla-Camps JC |
| Ref : Journal of Biological Chemistry , 264 :21401 , 1989 |
| Abstract : |
| PubMedSearch : le Du_1989_J.Biol.Chem_264_21401 |
| PubMedID: 2592383 |
| Title : Neurochemical and behavioral correlates of unilateral striatal acetylcholinesterase inhibition by fasciculin in rats - Bolioli_1989_Brain.Res_504_1 |
| Author(s) : Bolioli B , Castello ME , Jerusalinsky D , Rubinstein M , Medina J , Dajas F |
| Ref : Brain Research , 504 :1 , 1989 |
| Abstract : |
| PubMedSearch : Bolioli_1989_Brain.Res_504_1 |
| PubMedID: 2598003 |
| Title : Rat striatal acetylcholinesterase inhibition by fasciculin (a polypeptide from green mamba snake venom) - Dajas_1987_Neurosci.Lett_77_87 |
| Author(s) : Dajas F , Bolioli B , Castello ME , Silveira R |
| Ref : Neuroscience Letters , 77 :87 , 1987 |
| Abstract : |
| PubMedSearch : Dajas_1987_Neurosci.Lett_77_87 |
| PubMedID: 3601220 |
| Title : Fasciculin II, a protein inhibitor of acetylcholinesterase, tested on central synapses of Aplysia - Fossier_1986_Cell.Mol.Neurobiol_6_221 |
| Author(s) : Fossier P , Baux G , Tauc L |
| Ref : Cellular Molecular Neurobiology , 6 :221 , 1986 |
| Abstract : |
| PubMedSearch : Fossier_1986_Cell.Mol.Neurobiol_6_221 |
| PubMedID: 3731216 |
| Title : Anticholinesterase toxins - |
| Author(s) : Karlsson E , Mbugua PM , Rodriguez-Ithurralde D |
| Ref : Pharmacol Ther , 30 :259 , 1985 |
| PubMedID: 3842891 |
| Title : Effects of fasciculin 2, an anticholinesterase polypeptide from green mamba venom, on neuromuscular transmission in mouse diaphragm preparations - Anderson_1985_Neurosci.Lett_54_123 |
| Author(s) : Anderson AJ , Harvey AL , Mbugua PM |
| Ref : Neuroscience Letters , 54 :123 , 1985 |
| Abstract : |
| PubMedSearch : Anderson_1985_Neurosci.Lett_54_123 |
| PubMedID: 2986055 |
| Title : Fasciculins, anticholinesterase toxins from the venom of the green mamba Dendroaspis angusticeps - Karlsson_1984_J.Physiol.(Paris)_79_232 |
| Author(s) : Karlsson E , Mbugua PM , Rodriguez-Ithurralde D |
| Ref : Journal de Physiologie (Paris) , 79 :232 , 1984 |
| Abstract : |
| PubMedSearch : Karlsson_1984_J.Physiol.(Paris)_79_232 |
| PubMedID: 6530667 |