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3,3-dimethylbutylthioacetate_Y337A_human-ACHE

General

Gene_Locus EnzymeKmKcatExp. conditionsReference
human-BCHE D70G 9000 uM33200 /min  Lockridge_1990_Pharmacol.Ther_47_35

References (2)

Title : Contribution of aromatic moieties of tyrosine 133 and of the anionic subsite tryptophan 86 to catalytic efficiency and allosteric modulation of acetylcholinesterase - Ordentlich_1995_J.Biol.Chem_270_2082
Author(s) : Ordentlich A , Barak D , Kronman C , Ariel N , Segall Y , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 270 :2082 , 1995
PubMedID: 7836436

Title : Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket - Ordentlich_1993_J.Biol.Chem_268_17083
Author(s) : Ordentlich A , Barak D , Kronman C , Flashner Y , Leitner M , Segall Y , Ariel N , Cohen S , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 268 :17083 , 1993
PubMedID: 8349597
Gene_locus related to this paper: human-ACHE , human-BCHE