Gene_Locus | Enzyme | Km | Kcat | Exp. conditions | Reference |
---|---|---|---|---|---|
human-BCHE | D70G | 9000 uM | 33200 /min | Lockridge_1990_Pharmacol.Ther_47_35 |
Title : Contribution of aromatic moieties of tyrosine 133 and of the anionic subsite tryptophan 86 to catalytic efficiency and allosteric modulation of acetylcholinesterase - Ordentlich_1995_J.Biol.Chem_270_2082 |
Author(s) : Ordentlich A , Barak D , Kronman C , Ariel N , Segall Y , Velan B , Shafferman A |
Ref : Journal of Biological Chemistry , 270 :2082 , 1995 |
Abstract : |
PubMedSearch : Ordentlich_1995_J.Biol.Chem_270_2082 |
PubMedID: 7836436 |
Title : Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core - Barak_1994_J.Biol.Chem_269_6296 |
Author(s) : Barak D , Kronman C , Ordentlich A , Ariel N , Bromberg A , Marcus D , Lazar A , Velan B , Shafferman A |
Ref : Journal of Biological Chemistry , 269 :6296 , 1994 |
Abstract : |
PubMedSearch : Barak_1994_J.Biol.Chem_269_6296 |
PubMedID: 8119978 |
Title : Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center - Shafferman_1992_EMBO.J_11_3561 |
Author(s) : Shafferman A , Velan B , Ordentlich A , Kronman C , Grosfeld H , Leitner M , Flashner Y , Cohen S , Barak D , Ariel N |
Ref : EMBO Journal , 11 :3561 , 1992 |
Abstract : |
PubMedSearch : Shafferman_1992_EMBO.J_11_3561 |
PubMedID: 1396557 |