E470G_human-EPHX2

General

Gene Locus : No gene locus

Mode of mutation : Natural mutant

Disease :

Summary :

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : No torpedo number

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.E470G E470Gly is correlated with an increased risk of ischemic stroke in the African-American population, although the underlying molecular mechanism remains unclear.

References (2)

Title : Water will Find Its Way: Transport through Narrow Tunnels in Hydrolases - Sequeiros-Borja_2024_J.Chem.Inf.Model__
Author(s) : Sequeiros-Borja C , Surpeta B , Thirunavukarasu AS , Dongmo Foumthuim CJ , Marchlewski I , Brezovsky J
Ref : J Chem Inf Model , : , 2024
Abstract :
PubMedSearch : Sequeiros-Borja_2024_J.Chem.Inf.Model__
PubMedID: 38669675
Gene_locus related to this paper: canru-1lipa , rhoso-halo1 , soltu-3epoxy , human-EPHX2

Title : The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke - Fornage_2005_Hum.Mol.Genet_14_2829
Author(s) : Fornage M , Lee CR , Doris PA , Bray MS , Heiss G , Zeldin DC , Boerwinkle E
Ref : Hum Mol Genet , 14 :2829 , 2005
Abstract :
PubMedSearch : Fornage_2005_Hum.Mol.Genet_14_2829
PubMedID: 16115816
Gene_locus related to this paper: human-EPHX2