Brezovsky J

References (23)

Title : Water will Find Its Way: Transport through Narrow Tunnels in Hydrolases - Sequeiros-Borja_2024_J.Chem.Inf.Model__
Author(s) : Sequeiros-Borja C , Surpeta B , Thirunavukarasu AS , Dongmo Foumthuim CJ , Marchlewski I , Brezovsky J
Ref : J Chem Inf Model , : , 2024
PubMedID: 38669675
Gene_locus related to this paper: canru-1lipa , rhoso-halo1 , soltu-3epoxy , human-EPHX2

Title : Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17 - Chrast_2019_Microorganisms_7_
Author(s) : Chrast L , Tratsiak K , Planas-Iglesias J , Daniel L , Prudnikova T , Brezovsky J , Bednar D , Kuta Smatanova I , Chaloupkova R , Damborsky J
Ref : Microorganisms , 7 : , 2019
PubMedID: 31661858
Gene_locus related to this paper: 9alte-a3jb27

Title : Impact of the access tunnel engineering on catalysis is strictly ligand-specific - Kaushik_2018_FEBS.J_285_1456
Author(s) : Kaushik S , Marques SM , Khirsariya P , Paruch K , Libichova L , Brezovsky J , Prokop Z , Chaloupkova R , Damborsky J
Ref : Febs J , 285 :1456 , 2018
PubMedID: 29478278

Title : Different Structural Origins of the Enantioselectivity of Haloalkane Dehalogenases toward Linear beta-Haloalkanes: Open-Solvated versus Occluded-Desolvated Active Sites - Liskova_2017_Angew.Chem.Int.Ed.Engl_56_4719
Author(s) : Liskova V , Stepankova V , Bednar D , Brezovsky J , Prokop Z , Chaloupkova R , Damborsky J
Ref : Angew Chem Int Ed Engl , 56 :4719 , 2017
PubMedID: 28334478

Title : Catalytic Cycle of Haloalkane Dehalogenases Toward Unnatural Substrates Explored by Computational Modeling - Marques_2017_J.Chem.Inf.Model_57_1970
Author(s) : Marques SM , Dunajova Z , Prokop Z , Chaloupkova R , Brezovsky J , Damborsky J
Ref : J Chem Inf Model , 57 :1970 , 2017
PubMedID: 28696117

Title : Ancestral Haloalkane Dehalogenases Show Robustness and Unique Substrate Specificity - Babkova_2017_Chembiochem_18_1448
Author(s) : Babkova P , Sebestova E , Brezovsky J , Chaloupkova R , Damborsky J
Ref : Chembiochem , 18 :1448 , 2017
PubMedID: 28419658
Gene_locus related to this paper: 9bact-AncHLD5

Title : Discovery of Novel Haloalkane Dehalogenase Inhibitors - Buryska_2016_Appl.Environ.Microbiol_82_1958
Author(s) : Buryska T , Daniel L , Kunka A , Brezovsky J , Damborsky J , Prokop Z
Ref : Applied Environmental Microbiology , 82 :1958 , 2016
PubMedID: 26773086

Title : Engineering a de novo transport tunnel - Brezovsky_2016_ACS.Catal_6_7597
Author(s) : Brezovsky J , Babkova P , Degtjarik O , Fortova A , Gora A , Iermak I , Rezacova P , Dvorak P , Kuta-Smatanova I , Prokop Z , Chaloupkova R , Damborsky J
Ref : ACS Catal , 6 :7597 , 2016
PubMedID:
Gene_locus related to this paper: sphpi-linb

Title : Mechanism-based discovery of novel substrates of haloalkane dehalogenases using in silico screening - Daniel_2015_J.Chem.Inf.Model_55_54
Author(s) : Daniel L , Buryska T , Prokop Z , Damborsky J , Brezovsky J
Ref : J Chem Inf Model , 55 :54 , 2015
PubMedID: 25495415

Title : Site-specific analysis of protein hydration based on unnatural amino acid fluorescence - Amaro_2015_J.Am.Chem.Soc_137_4988
Author(s) : Amaro M , Brezovsky J , Kovacova S , Sykora J , Bednar D , Nemec V , Liskova V , Kurumbang NP , Beerens K , Chaloupkova R , Paruch K , Hof M , Damborsky J
Ref : Journal of the American Chemical Society , 137 :4988 , 2015
PubMedID: 25815779

Title : FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants - Bednar_2015_PLoS.Comput.Biol_11_e1004556
Author(s) : Bednar D , Beerens K , Sebestova E , Bendl J , Khare S , Chaloupkova R , Prokop Z , Brezovsky J , Baker D , Damborsky J
Ref : PLoS Comput Biol , 11 :e1004556 , 2015
PubMedID: 26529612
Gene_locus related to this paper: rhoso-halo1

Title : Balancing the stability-activity trade-off by fine-tuning dehalogenase access tunnels - Liskova_2015_ChemCatChem_7_648
Author(s) : Liskova V , Bednar D , Prudnikova T , Rezacova P , Koudelakova T , Sebestova E , Kuta-Smatanova I , Brezovsky J , Chaloupkova R , Damborsky J
Ref : ChemCatChem , 7 :648 , 2015
PubMedID:
Gene_locus related to this paper: rhoso-halo1

Title : Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites - Chaloupkova_2014_Acta.Crystallogr.D.Biol.Crystallogr_70_1884
Author(s) : Chaloupkova R , Prudnikova T , Rezacova P , Prokop Z , Koudelakova T , Daniel L , Brezovsky J , Ikeda-Ohtsubo W4 , Sato Y , Kuty M , Nagata Y , Kuta Smatanova I , Damborsky J
Ref : Acta Crystallographica D Biol Crystallogr , 70 :1884 , 2014
PubMedID: 25004965
Gene_locus related to this paper: brael-e2rv62

Title : Dynamics and hydration explain failed functional transformation in dehalogenase design - Sykora_2014_Nat.Chem.Biol_10_428
Author(s) : Sykora J , Brezovsky J , Koudelakova T , Lahoda M , Fortova A , Chernovets T , Chaloupkova R , Stepankova V , Prokop Z , Smatanova IK , Hof M , Damborsky J
Ref : Nat Chemical Biology , 10 :428 , 2014
PubMedID: 24727901
Gene_locus related to this paper: rhoso-halo1

Title : The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 - Hasan_2013_FEBS.J_280_3149
Author(s) : Hasan K , Gora A , Brezovsky J , Chaloupkova R , Moskalikova H , Fortova A , Nagata Y , Damborsky J , Prokop Z
Ref : Febs J , 280 :3149 , 2013
PubMedID: 23490078

Title : Are time-dependent fluorescence shifts at the tunnel mouth of haloalkane dehalogenase enzymes dependent on the choice of the chromophore? - Amaro_2013_J.Phys.Chem.B_117_7898
Author(s) : Amaro M , Brezovsky J , Kovacova S , Maier L , Chaloupkova R , Sykora J , Paruch K , Damborsky J , Hof M
Ref : J Phys Chem B , 117 :7898 , 2013
PubMedID: 23781851

Title : Interaction of organic solvents with protein structures at protein-solvent interface - Khabiri_2013_J.Mol.Model_19_4701
Author(s) : Khabiri M , Minofar B , Brezovsky J , Damborsky J , Ettrich R
Ref : J Mol Model , 19 :4701 , 2013
PubMedID: 22760789

Title : Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel - Koudelakova_2013_Angew.Chem.Int.Ed.Engl_52_1959
Author(s) : Koudelakova T , Chaloupkova R , Brezovsky J , Prokop Z , Sebestova E , Hesseler M , Khabiri M , Plevaka M , Kulik D , Kuta Smatanova I , Rezacova P , Ettrich R , Bornscheuer UT , Damborsky J
Ref : Angew Chem Int Ed Engl , 52 :1959 , 2013
PubMedID: 23303607
Gene_locus related to this paper: rhoso-halo1

Title : Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents - Stepankova_2013_Chembiochem_14_890
Author(s) : Stepankova V , Khabiri M , Brezovsky J , Pavelka A , Sykora J , Amaro M , Minofar B , Prokop Z , Hof M , Ettrich R , Chaloupkova R , Damborsky J
Ref : Chembiochem , 14 :890 , 2013
PubMedID: 23564727
Gene_locus related to this paper: rhoso-halo1

Title : Substrate specificity of haloalkane dehalogenases - Koudelakova_2011_Biochem.J_435_345
Author(s) : Koudelakova T , Chovancova E , Brezovsky J , Monincova M , Fortova A , Jarkovsky J , Damborsky J
Ref : Biochemical Journal , 435 :345 , 2011
PubMedID: 21294712
Gene_locus related to this paper: agrtu-DHAA , brael-e2rv62 , braja-dhaa , myctu-linb , myctu-Rv1833c , rhoba-DHLA , rhoso-halo1 , sphpi-linb , xanau-halo1

Title : Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering -
Author(s) : Prokop Z , Sato Y , Brezovsky J , Mozga T , Chaloupkova R , Koudelakova T , Jerabek P , Stepankova V , Natsume R , van Leeuwen JG , Janssen DB , Florian J , Nagata Y , Senda T , Damborsky J
Ref : Angew Chem Int Ed Engl , 49 :6111 , 2010
PubMedID: 20645368
Gene_locus related to this paper: braja-dhaa

Title : Computational tools for designing and engineering biocatalysts - Damborsky_2009_Curr.Opin.Chem.Biol_13_26
Author(s) : Damborsky J , Brezovsky J
Ref : Curr Opin Chemical Biology , 13 :26 , 2009
PubMedID: 19297237

Title : Nanosecond time-dependent Stokes shift at the tunnel mouth of haloalkane dehalogenases - Jesenska_2009_J.Am.Chem.Soc_131_494
Author(s) : Jesenska A , Sykora J , Olzynska A , Brezovsky J , Zdrahal Z , Damborsky J , Hof M
Ref : Journal of the American Chemical Society , 131 :494 , 2009
PubMedID: 19113888