Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : PROSS algorithm Expression in E Coli Brazzolotto_2017_Molecules_22_
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure : 6EMI
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Expression in E Coli || PROSS algorithm
Torpedo_number : 419
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.F417Y Phe417Tyr (p.F445Y Phe445Tyr in primary sequence with 28 amino-acids signal peptide) Mutation designed by -Protein Repair One Stop Shop- process for the production of active human butyrylcholinesterase in a prokaryotic system. The mutation gives Tyr as in ACHE of Torpedo californica, human, mouse, and Bungarus fasciatus
| Title : Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development - Brazzolotto_2017_Molecules_22_ |
| Author(s) : Brazzolotto X , Igert A , Guillon V , Santoni G , Nachon F |
| Ref : Molecules , 22 : , 2017 |
| Abstract : |
| PubMedSearch : Brazzolotto_2017_Molecules_22_ |
| PubMedID: 29077024 |
| Gene_locus related to this paper: human-BCHE |