Igert A

References (30)

Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__
Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S
Ref : Journal of Medicinal Chemistry , : , 2025
Abstract :
PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__
PubMedID: 40779804

Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__
Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S
Ref : Journal of Medicinal Chemistry , : , 2025
Abstract :
PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__
PubMedID: 40779804

Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681
Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S
Ref : Chemico-Biological Interactions , 420 :111681 , 2025
Abstract :
PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681
PubMedID: 40750068
Gene_locus related to this paper: human-BCHE

Title : Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670
Author(s) : Kosak U , Knez D , Benetik SF , Sokolov PM , Pislar A , Horvat S , Stojan J , Lv B , Zhang W , Wang Y , Wang Q , Igert A , Dias J , Nachon F , Brazzolotto X , Sun H , Gobec S
Ref : Chemico-Biological Interactions , 420 :111670 , 2025
Abstract :
PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670
PubMedID: 40712769
Gene_locus related to this paper: human-BCHE

Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681
Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S
Ref : Chemico-Biological Interactions , 420 :111681 , 2025
Abstract :
PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681
PubMedID: 40750068
Gene_locus related to this paper: human-BCHE

Title : Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670
Author(s) : Kosak U , Knez D , Benetik SF , Sokolov PM , Pislar A , Horvat S , Stojan J , Lv B , Zhang W , Wang Y , Wang Q , Igert A , Dias J , Nachon F , Brazzolotto X , Sun H , Gobec S
Ref : Chemico-Biological Interactions , 420 :111670 , 2025
Abstract :
PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670
PubMedID: 40712769
Gene_locus related to this paper: human-BCHE

Title : N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681
Author(s) : Kosak U , Knez D , Pislar A , Horvat S , Zakelj S , Igert A , Dias J , Nachon F , Brazzolotto X , Gobec S
Ref : Chemico-Biological Interactions , 420 :111681 , 2025
Abstract :
PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111681
PubMedID: 40750068
Gene_locus related to this paper: human-BCHE

Title : Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease - Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670
Author(s) : Kosak U , Knez D , Benetik SF , Sokolov PM , Pislar A , Horvat S , Stojan J , Lv B , Zhang W , Wang Y , Wang Q , Igert A , Dias J , Nachon F , Brazzolotto X , Sun H , Gobec S
Ref : Chemico-Biological Interactions , 420 :111670 , 2025
Abstract :
PubMedSearch : Kosak_2025_Chem.Biol.Interact_15ChEPon_420_111670
PubMedID: 40712769
Gene_locus related to this paper: human-BCHE

Title : Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38alpha Mitogen-Activated Protein Kinase Inhibitors - Ferjancic Benetik_2025_J.Med.Chem__
Author(s) : Ferjancic Benetik S , Proj M , Knez D , Kosak U , Meden A , Krajsek K , Pislar A , Horvat S , Svajger U , Tesic N , Pulkrabkova L , Soukup O , Skarka A , Andrys R , Brazzolotto X , Igert A , Nachon F , Dias J , Detka J , Gdula-Argasinska J , Wyska E , Szafarz M , Manik A , Plachtij N , Musilek K , Salat K , Obreza A , Gobec S
Ref : Journal of Medicinal Chemistry , : , 2025
Abstract :
PubMedSearch : Ferjancic Benetik_2025_J.Med.Chem__
PubMedID: 40779804

Title : Characterization of four BCHE mutations associated with prolonged effect of suxamethonium - Brazzolotto_2021_Pharmacogenomics.J_21_165
Author(s) : Brazzolotto X , Courcelle S , Sauvanet C , Guillon V , Igert A , Kononchik J , Nachon F , Ceppa F , Delacour H
Ref : Pharmacogenomics J , 21(2):165-173 : , 2021
Abstract :
PubMedSearch : Brazzolotto_2021_Pharmacogenomics.J_21_165
PubMedID: 33024248

Title : Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database - Miles_2021_Chem.Biol.Drug.Des__
Author(s) : Miles JA , Ng JH , Sreenivas BY , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP
Ref : Chemical Biology Drug Des , : , 2021
Abstract :
PubMedSearch : Miles_2021_Chem.Biol.Drug.Des__
PubMedID: 33455074

Title : Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database - Miles_2021_Chem.Biol.Drug.Des__
Author(s) : Miles JA , Ng JH , Sreenivas BY , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP
Ref : Chemical Biology Drug Des , : , 2021
Abstract :
PubMedSearch : Miles_2021_Chem.Biol.Drug.Des__
PubMedID: 33455074

Title : Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice - Maupu_2021_Neurobiol.Dis__105276
Author(s) : Maupu C , Enderlin J , Igert A , Oger M , Auvin S , Hassan-Abdi R , Soussi-Yanicostas N , Brazzolotto X , Nachon F , Bo GD , Dupuis N
Ref : Neurobiol Dis , :105276 , 2021
Abstract :
PubMedSearch : Maupu_2021_Neurobiol.Dis__105276
PubMedID: 33529768

Title : Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice - Maupu_2021_Neurobiol.Dis__105276
Author(s) : Maupu C , Enderlin J , Igert A , Oger M , Auvin S , Hassan-Abdi R , Soussi-Yanicostas N , Brazzolotto X , Nachon F , Bo GD , Dupuis N
Ref : Neurobiol Dis , :105276 , 2021
Abstract :
PubMedSearch : Maupu_2021_Neurobiol.Dis__105276
PubMedID: 33529768

Title : Characterization of four BCHE mutations associated with prolonged effect of suxamethonium - Brazzolotto_2021_Pharmacogenomics.J_21_165
Author(s) : Brazzolotto X , Courcelle S , Sauvanet C , Guillon V , Igert A , Kononchik J , Nachon F , Ceppa F , Delacour H
Ref : Pharmacogenomics J , 21(2):165-173 : , 2021
Abstract :
PubMedSearch : Brazzolotto_2021_Pharmacogenomics.J_21_165
PubMedID: 33024248

Title : Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database - Miles_2021_Chem.Biol.Drug.Des__
Author(s) : Miles JA , Ng JH , Sreenivas BY , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP
Ref : Chemical Biology Drug Des , : , 2021
Abstract :
PubMedSearch : Miles_2021_Chem.Biol.Drug.Des__
PubMedID: 33455074

Title : Characterization of four BCHE mutations associated with prolonged effect of suxamethonium - Brazzolotto_2021_Pharmacogenomics.J_21_165
Author(s) : Brazzolotto X , Courcelle S , Sauvanet C , Guillon V , Igert A , Kononchik J , Nachon F , Ceppa F , Delacour H
Ref : Pharmacogenomics J , 21(2):165-173 : , 2021
Abstract :
PubMedSearch : Brazzolotto_2021_Pharmacogenomics.J_21_165
PubMedID: 33024248

Title : Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice - Maupu_2021_Neurobiol.Dis__105276
Author(s) : Maupu C , Enderlin J , Igert A , Oger M , Auvin S , Hassan-Abdi R , Soussi-Yanicostas N , Brazzolotto X , Nachon F , Bo GD , Dupuis N
Ref : Neurobiol Dis , :105276 , 2021
Abstract :
PubMedSearch : Maupu_2021_Neurobiol.Dis__105276
PubMedID: 33529768

Title : Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death - Brenet_2020_Sci.Rep_10_19228
Author(s) : Brenet A , Somkhit J , Hassan-Abdi R , Yanicostas C , Romain C , Bar O , Igert A , Saurat D , Taudon N , Dal Bo G , Nachon F , Dupuis N , Soussi-Yanicostas N
Ref : Sci Rep , 10 :19228 , 2020
Abstract :
PubMedSearch : Brenet_2020_Sci.Rep_10_19228
PubMedID: 33154418
Gene_locus related to this paper: danre-ACHE

Title : Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death - Brenet_2020_Sci.Rep_10_19228
Author(s) : Brenet A , Somkhit J , Hassan-Abdi R , Yanicostas C , Romain C , Bar O , Igert A , Saurat D , Taudon N , Dal Bo G , Nachon F , Dupuis N , Soussi-Yanicostas N
Ref : Sci Rep , 10 :19228 , 2020
Abstract :
PubMedSearch : Brenet_2020_Sci.Rep_10_19228
PubMedID: 33154418
Gene_locus related to this paper: danre-ACHE

Title : Characterization of organophosphate-induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure - Enderlin_2020_Epilepsia__
Author(s) : Enderlin J , Igert A , Auvin S , Nachon F , Dal Bo G , Dupuis N
Ref : Epilepsia , : , 2020
Abstract :
PubMedSearch : Enderlin_2020_Epilepsia__
PubMedID: 32359085

Title : Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death - Brenet_2020_Sci.Rep_10_19228
Author(s) : Brenet A , Somkhit J , Hassan-Abdi R , Yanicostas C , Romain C , Bar O , Igert A , Saurat D , Taudon N , Dal Bo G , Nachon F , Dupuis N , Soussi-Yanicostas N
Ref : Sci Rep , 10 :19228 , 2020
Abstract :
PubMedSearch : Brenet_2020_Sci.Rep_10_19228
PubMedID: 33154418
Gene_locus related to this paper: danre-ACHE

Title : Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening - Miles_2020_Bioorg.Med.Chem.Lett__127609
Author(s) : Miles JA , Kapure JS , Singh Deora G , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP
Ref : Bioorganic & Medicinal Chemistry Lett , :127609 , 2020
Abstract :
PubMedSearch : Miles_2020_Bioorg.Med.Chem.Lett__127609
PubMedID: 33039562

Title : Characterization of organophosphate-induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure - Enderlin_2020_Epilepsia__
Author(s) : Enderlin J , Igert A , Auvin S , Nachon F , Dal Bo G , Dupuis N
Ref : Epilepsia , : , 2020
Abstract :
PubMedSearch : Enderlin_2020_Epilepsia__
PubMedID: 32359085

Title : Characterization of organophosphate-induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure - Enderlin_2020_Epilepsia__
Author(s) : Enderlin J , Igert A , Auvin S , Nachon F , Dal Bo G , Dupuis N
Ref : Epilepsia , : , 2020
Abstract :
PubMedSearch : Enderlin_2020_Epilepsia__
PubMedID: 32359085

Title : Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening - Miles_2020_Bioorg.Med.Chem.Lett__127609
Author(s) : Miles JA , Kapure JS , Singh Deora G , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP
Ref : Bioorganic & Medicinal Chemistry Lett , :127609 , 2020
Abstract :
PubMedSearch : Miles_2020_Bioorg.Med.Chem.Lett__127609
PubMedID: 33039562

Title : Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening - Miles_2020_Bioorg.Med.Chem.Lett__127609
Author(s) : Miles JA , Kapure JS , Singh Deora G , Courageux C , Igert A , Dias J , McGeary RP , Brazzolotto X , Ross BP
Ref : Bioorganic & Medicinal Chemistry Lett , :127609 , 2020
Abstract :
PubMedSearch : Miles_2020_Bioorg.Med.Chem.Lett__127609
PubMedID: 33039562

Title : Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development - Brazzolotto_2017_Molecules_22_
Author(s) : Brazzolotto X , Igert A , Guillon V , Santoni G , Nachon F
Ref : Molecules , 22 : , 2017
Abstract :
PubMedSearch : Brazzolotto_2017_Molecules_22_
PubMedID: 29077024
Gene_locus related to this paper: human-BCHE

Title : Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development - Brazzolotto_2017_Molecules_22_
Author(s) : Brazzolotto X , Igert A , Guillon V , Santoni G , Nachon F
Ref : Molecules , 22 : , 2017
Abstract :
PubMedSearch : Brazzolotto_2017_Molecules_22_
PubMedID: 29077024
Gene_locus related to this paper: human-BCHE

Title : Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development - Brazzolotto_2017_Molecules_22_
Author(s) : Brazzolotto X , Igert A , Guillon V , Santoni G , Nachon F
Ref : Molecules , 22 : , 2017
Abstract :
PubMedSearch : Brazzolotto_2017_Molecules_22_
PubMedID: 29077024
Gene_locus related to this paper: human-BCHE