Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Search for phosphotriesterase activity Phosphotriesterase activity No catalytic activity Millard_1995_Biochemistry_34_15925 Lockridge_1997_Biochemistry_36_786
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Search for phosphotriesterase activity
Torpedo_number : 123
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.G121H Gly121His (p.G149H Gly149His in primary sequence with 28 amino-acids signal peptide) no Phosphotriesterase activity
Title : A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase - Lockridge_1997_Biochemistry_36_786 |
Author(s) : Lockridge O , Blong RM , Masson P , Froment MT , Millard CB , Broomfield CA |
Ref : Biochemistry , 36 :786 , 1997 |
Abstract : |
PubMedSearch : Lockridge_1997_Biochemistry_36_786 |
PubMedID: 9020776 |
Title : Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase - Millard_1995_Biochemistry_34_15925 |
Author(s) : Millard CB , Lockridge O , Broomfield CA |
Ref : Biochemistry , 34 :15925 , 1995 |
Abstract : |
PubMedSearch : Millard_1995_Biochemistry_34_15925 |
PubMedID: 8519749 |