Y124H_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Search for phosphotriesterase activity Phosphotriesterase activity Trovaslet-Leroy_2011_Toxicol.Lett_206_14

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Search for phosphotriesterase activity

Torpedo_number : 121

Kinetic Parameter : No kinetic parameter

News : JUNE-24-2011

Comment :
p.Y124H Tyr124His (p.Y155H Tyr155His in primary sequence with 31 amino-acids signal peptide) Search for phosphotriesterase activity\;Phosphotriesterase activity

References (1)

Title : Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents - Trovaslet-Leroy_2011_Toxicol.Lett_206_14
Author(s) : Trovaslet-Leroy M , Musilova L , Renault F , Brazzolotto X , Misik J , Novotny L , Froment MT , Gillon E , Loiodice M , Verdier L , Masson P , Rochu D , Jun D , Nachon F
Ref : Toxicol Lett , 206 :14 , 2011
PubMedID: 21683774