| Title : Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase - Kliachyna_2014_Eur.J.Med.Chem_78C_455 |
| Author(s) : Kliachyna M , Santoni G , Nussbaum V , Renou J , Sanson B , Colletier JP , Arboleas M , Loiodice M , Weik M , Jean L , Renard PY , Nachon F , Baati R |
| Ref : Eur Journal of Medicinal Chemistry , 78C :455 , 2014 |
| Abstract : |
| PubMedSearch : Kliachyna_2014_Eur.J.Med.Chem_78C_455 |
| PubMedID: 24704618 |
| Title : Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterases - Renou_2014_Chem.Commun.(Camb)_50_3947 |
| Author(s) : Renou J , Loiodice M , Arboleas M , Baati R , Jean L , Nachon F , Renard PY |
| Ref : Chem Commun (Camb) , 50 :3947 , 2014 |
| Abstract : |
| PubMedSearch : Renou_2014_Chem.Commun.(Camb)_50_3947 |
| PubMedID: 24599312 |
| Title : A step toward the reactivation of aged cholinesterases - Crystal structure of ligands binding to aged human butyrylcholinesterase - Wandhammer_2013_Chem.Biol.Interact_203_19 |
| Author(s) : Wandhammer M , De Koning MC , van Grol M , Loiodice M , Saurel L , Noort D , Goeldner M , Nachon F |
| Ref : Chemico-Biological Interactions , 203 :19 , 2013 |
| Abstract : |
| PubMedSearch : Wandhammer_2013_Chem.Biol.Interact_203_19 |
| PubMedID: 22922115 |
| Gene_locus related to this paper: human-BCHE |
| Title : Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents - Renou_2013_Chem.Biol.Interact_203_81 |
| Author(s) : Renou J , Mercey G , Verdelet T , Paunescu E , Gillon E , Arboleas M , Loiodice M , Kliachyna M , Baati R , Nachon F , Jean L , Renard PY |
| Ref : Chemico-Biological Interactions , 203 :81 , 2013 |
| Abstract : |
| PubMedSearch : Renou_2013_Chem.Biol.Interact_203_81 |
| PubMedID: 23111374 |
| Title : Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase - Mercey_2012_J.Med.Chem_55_10791 |
| Author(s) : Mercey G , Renou J , Verdelet T , Kliachyna M , Baati R , Gillon E , Arboleas M , Loiodice M , Nachon F , Jean L , Renard PY |
| Ref : Journal of Medicinal Chemistry , 55 :10791 , 2012 |
| Abstract : |
| PubMedSearch : Mercey_2012_J.Med.Chem_55_10791 |
| PubMedID: 23148598 |
| Title : Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents - Trovaslet-Leroy_2011_Toxicol.Lett_206_14 |
| Author(s) : Trovaslet-Leroy M , Musilova L , Renault F , Brazzolotto X , Misik J , Novotny L , Froment MT , Gillon E , Loiodice M , Verdier L , Masson P , Rochu D , Jun D , Nachon F |
| Ref : Toxicol Lett , 206 :14 , 2011 |
| Abstract : |
| PubMedSearch : Trovaslet-Leroy_2011_Toxicol.Lett_206_14 |
| PubMedID: 21683774 |
| Title : Preparation and characterization of methoxy polyethylene glycol-conjugated phosphotriesterase as a potential catalytic bioscavenger against organophosphate poisoning - Jun_2010_Chem.Biol.Interact_187_380 |
| Author(s) : Jun D , Musilova L , Link M , Loiodice M , Nachon F , Rochu D , Renault F , Masson P |
| Ref : Chemico-Biological Interactions , 187 :380 , 2010 |
| Abstract : |
| PubMedSearch : Jun_2010_Chem.Biol.Interact_187_380 |
| PubMedID: 20230809 |
| Title : Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. - Carletti_2009_Biochem.J_421_97 |
| Author(s) : Carletti E , Aurbek N , Gillon E , Loiodice M , Nicolet Y , Fontecilla-Camps JC , Masson P , Thiermann H , Nachon F , Worek F |
| Ref : Biochemical Journal , 421 :97 , 2009 |
| Abstract : |
| PubMedSearch : Carletti_2009_Biochem.J_421_97 |
| PubMedID: 19368529 |
| Gene_locus related to this paper: human-BCHE |
| Title : Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation - Carletti_2008_J.Am.Chem.Soc_130_16011 |
| Author(s) : Carletti E , Li H , Li B , Ekstrom F , Nicolet Y , Loiodice M , Gillon E , Froment MT , Lockridge O , Schopfer LM , Masson P , Nachon F |
| Ref : Journal of the American Chemical Society , 130 :16011 , 2008 |
| Abstract : |
| PubMedSearch : Carletti_2008_J.Am.Chem.Soc_130_16011 |
| PubMedID: 18975951 |
| Gene_locus related to this paper: human-BCHE , mouse-ACHE |
| Title : Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters - Poyot_2006_Biochim.Biophys.Acta_1764_1470 |
| Author(s) : Poyot T , Nachon F , Froment MT , Loiodice M , Wieseler S , Schopfer LM , Lockridge O , Masson P |
| Ref : Biochimica & Biophysica Acta , 1764 :1470 , 2006 |
| Abstract : |
| PubMedSearch : Poyot_2006_Biochim.Biophys.Acta_1764_1470 |
| PubMedID: 16962835 |