Y337G_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Substrate activation Substrate activation at low and high Ph Masson_2002_Biochim.Biophys.Acta_1594_313 || Signal transduction Substrate activation at low and high Ph Masson_2002_Biochim.Biophys.Acta_1594_313

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Substrate activation || Signal transduction

Torpedo_number : 330

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.Y337G Tyr337Gly (p.Y368G Tyr368Gly in primary sequence with 31 amino-acids signal peptide) Signal transduction, Substrate activation at low and high Ph

References (1)

Title : Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite - Masson_2002_Biochim.Biophys.Acta_1594_313
Author(s) : Masson P , Schopfer LM , Bartels CF , Froment MT , Ribes F , Nachon F , Lockridge O
Ref : Biochimica & Biophysica Acta , 1594 :313 , 2002
PubMedID: 11904227