Gene Locus : human-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Substrate activation Substrate activation at low Ph inhibition at high Masson_2002_Biochim.Biophys.Acta_1594_313 || Signal transduction Substrate activation at low Ph inhibition at high Masson_2002_Biochim.Biophys.Acta_1594_313
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Substrate activation || Signal transduction
Torpedo_number : 330
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.Y337W Tyr337Trp (p.Y368W Tyr368Trp in primary sequence with 31 amino-acids signal peptide) Signal transduction, Substrate activation at low Ph inhibition at high Ph
| Title : Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite - Masson_2002_Biochim.Biophys.Acta_1594_313 |
| Author(s) : Masson P , Schopfer LM , Bartels CF , Froment MT , Ribes F , Nachon F , Lockridge O |
| Ref : Biochimica & Biophysica Acta , 1594 :313 , 2002 |
| Abstract : |
| PubMedSearch : Masson_2002_Biochim.Biophys.Acta_1594_313 |
| PubMedID: 11904227 |