| Title : Covalent attachment of antagonists to the alpha7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides - Ambrus_2012_Chem.Commun.(Camb)_48_6699 |
| Author(s) : Ambrus JI , Halliday JI , Kanizaj N , Absalom N , Harpsoe K , Balle T , Chebib M , McLeod MD |
| Ref : Chem Commun (Camb) , 48 :6699 , 2012 |
|
Abstract :
The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the alpha7 nicotinic acetylcholine receptor (nAChR). |
| PubMedSearch : Ambrus_2012_Chem.Commun.(Camb)_48_6699 |
| PubMedID: 22627701 |
Ambrus JI, Halliday JI, Kanizaj N, Absalom N, Harpsoe K, Balle T, Chebib M, McLeod MD (2012)
Covalent attachment of antagonists to the alpha7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides
Chem Commun (Camb)
48 :6699
Ambrus JI, Halliday JI, Kanizaj N, Absalom N, Harpsoe K, Balle T, Chebib M, McLeod MD (2012)
Chem Commun (Camb)
48 :6699