Harpsoe K

References (11)

Title : GPCRdb: the G protein-coupled receptor database - an introduction - Munk_2016_Br.J.Pharmacol_173_2195
Author(s) : Munk C , Isberg V , Mordalski S , Harpsoe K , Rataj K , Hauser AS , Kolb P , Bojarski AJ , Vriend G , Gloriam DE
Ref : British Journal of Pharmacology , 173 :2195 , 2016
Abstract :
PubMedSearch : Munk_2016_Br.J.Pharmacol_173_2195
PubMedID: 27155948

Title : Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors - Harpsoe_2013_J.Biol.Chem_288_2559
Author(s) : Harpsoe K , Hald H , Timmermann DB , Jensen ML , Dyhring T , Nielsen EO , Peters D , Balle T , Gajhede M , Kastrup JS , Ahring PK
Ref : Journal of Biological Chemistry , 288 :2559 , 2013
Abstract :
PubMedSearch : Harpsoe_2013_J.Biol.Chem_288_2559
PubMedID: 23229547

Title : Covalent trapping of methyllycaconitine at the alpha4-alpha4 interface of the alpha4beta2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed - Absalom_2013_J.Biol.Chem_288_26521
Author(s) : Absalom NL , Quek G , Lewis TM , Qudah T , von Arenstorff I , Ambrus JI , Harpsoe K , Karim N , Balle T , McLeod MD , Chebib M
Ref : Journal of Biological Chemistry , 288 :26521 , 2013
Abstract :
PubMedSearch : Absalom_2013_J.Biol.Chem_288_26521
PubMedID: 23893416

Title : Poster: An additional binding site for methyllycaconitine (MLA) and analogs occurs at the alpha4-alpha4 interface of the (alpha4)3(beta2)2 nAChR -
Author(s) : Chebib M , Absalom NL , Quek G , Indurthi DC , Lewis TM , Qudah T , von Arenstorff I , Halliday JI , Ambrus JI , Harpsoe K , Karim N , Balle T , McLeod MD
Ref : Biochemical Pharmacology , 86 :1225 , 2013
PubMedID:

Title : Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site - Trattnig_2012_J.Biol.Chem_287_25241
Author(s) : Trattnig SM , Harpsoe K , Thygesen SB , Rahr LM , Ahring PK , Balle T , Jensen AA
Ref : Journal of Biological Chemistry , 287 :25241 , 2012
Abstract :
PubMedSearch : Trattnig_2012_J.Biol.Chem_287_25241
PubMedID: 22589534

Title : Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: unique role of halogen bonding revealed - Rohde_2012_J.Biol.Chem_287_4248
Author(s) : Rohde LA , Ahring PK , Jensen ML , Nielsen EO , Peters D , Helgstrand C , Krintel C , Harpsoe K , Gajhede M , Kastrup JS , Balle T
Ref : Journal of Biological Chemistry , 287 :4248 , 2012
Abstract :
PubMedSearch : Rohde_2012_J.Biol.Chem_287_4248
PubMedID: 22170047

Title : Covalent attachment of antagonists to the alpha7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides - Ambrus_2012_Chem.Commun.(Camb)_48_6699
Author(s) : Ambrus JI , Halliday JI , Kanizaj N , Absalom N , Harpsoe K , Balle T , Chebib M , McLeod MD
Ref : Chem Commun (Camb) , 48 :6699 , 2012
Abstract :
PubMedSearch : Ambrus_2012_Chem.Commun.(Camb)_48_6699
PubMedID: 22627701

Title : Poster: The (alpha4)3(\/beta2)2 nAChR has a benzodiazepine-like modulatory binding site in the alphaalpha-subunit interface as revealed by studies with NS9283 -
Author(s) : Ahring PK , Peters D , Christensen JK , Jensen ML , Harpsoe K , Balle T
Ref : Biochemical Pharmacology , 82 :1029 , 2011
PubMedID:

Title : Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors - Harpsoe_2011_J.Neurosci_31_10759
Author(s) : Harpsoe K , Ahring PK , Christensen JK , Jensen ML , Peters D , Balle T
Ref : Journal of Neuroscience , 31 :10759 , 2011
Abstract :
PubMedSearch : Harpsoe_2011_J.Neurosci_31_10759
PubMedID: 21795528

Title : Complementary three-dimensional quantitative structure-activity relationship modeling of binding affinity and functional potency: a study on alpha4beta2 nicotinic ligands - Tosco_2009_J.Med.Chem_52_2311
Author(s) : Tosco P , Ahring PK , Dyhring T , Peters D , Harpsoe K , Liljefors T , Balle T
Ref : Journal of Medicinal Chemistry , 52 :2311 , 2009
Abstract :
PubMedSearch : Tosco_2009_J.Med.Chem_52_2311
PubMedID: 19301898

Title : Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives - Armishaw_2009_J.Biol.Chem_284_9498
Author(s) : Armishaw C , Jensen AA , Balle T , Clark RJ , Harpsoe K , Skonberg C , Liljefors T , Stromgaard K
Ref : Journal of Biological Chemistry , 284 :9498 , 2009
Abstract :
PubMedSearch : Armishaw_2009_J.Biol.Chem_284_9498
PubMedID: 19131337