Dieterich_2008_Nat.Genet_40_1193

Reference

Title : The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism - Dieterich_2008_Nat.Genet_40_1193
Author(s) : Dieterich C , Clifton SW , Schuster LN , Chinwalla A , Delehaunty K , Dinkelacker I , Fulton L , Fulton R , Godfrey J , Minx P , Mitreva M , Roeseler W , Tian H , Witte H , Yang SP , Wilson RK , Sommer RJ
Ref : Nat Genet , 40 :1193 , 2008
Abstract :

Here we present a draft genome sequence of the nematode Pristionchus pacificus, a species that is associated with beetles and is used as a model system in evolutionary biology. With 169 Mb and 23,500 predicted protein-coding genes, the P. pacificus genome is larger than those of Caenorhabditis elegans and the human parasite Brugia malayi. Compared to C. elegans, the P. pacificus genome has more genes encoding cytochrome P450 enzymes, glucosyltransferases, sulfotransferases and ABC transporters, many of which were experimentally validated. The P. pacificus genome contains genes encoding cellulase and diapausin, and cellulase activity is found in P. pacificus secretions, indicating that cellulases can be found in nematodes beyond plant parasites. The relatively higher number of detoxification and degradation enzymes in P. pacificus is consistent with its necromenic lifestyle and might represent a preadaptation for parasitism. Thus, comparative genomics analysis of three ecologically distinct nematodes offers a unique opportunity to investigate the association between genome structure and lifestyle.

PubMedSearch : Dieterich_2008_Nat.Genet_40_1193
PubMedID: 18806794
Gene_locus related to this paper: pripa-h3dz72 , pripa-h3dzd7 , pripa-h3epg7 , pripa-h3ept4 , pripa-h3ept8 , pripa-h3ew78 , pripa-h3ext9 , pripa-h3f0j4 , pripa-h3f919 , pripa-h3f920 , pripa-h3fcj7 , pripa-h3fg45 , pripa-h3fg46 , pripa-h3fg51.2 , pripa-h3fhh1 , pripa-h3fhv6 , pripa-h3fig0 , pripa-h3fj25 , pripa-h3fvb4 , pripa-h3g1q9 , pripa-h3g217 , pripa-a0a0f5cf17 , pripa-a0a0f5crg5 , pripa-a0a0f5csq7 , pripa-h3esz7 , pripa-a0a0f5chi5 , pripa-h3fh18 , pripa-h3dzn5

Related information

Gene_locus pripa-h3dz72    pripa-h3dzd7    pripa-h3epg7    pripa-h3ept4    pripa-h3ept8    pripa-h3ew78    pripa-h3ext9    pripa-h3f0j4    pripa-h3f919    pripa-h3f920    pripa-h3fcj7    pripa-h3fg45    pripa-h3fg46    pripa-h3fg51.2    pripa-h3fhh1    pripa-h3fhv6    pripa-h3fig0    pripa-h3fj25    pripa-h3fvb4    pripa-h3g1q9    pripa-h3g217    pripa-a0a0f5cf17    pripa-a0a0f5crg5    pripa-a0a0f5csq7    pripa-h3esz7    pripa-a0a0f5chi5    pripa-h3fh18    pripa-h3dzn5
Gene_locus_frgt pripa-h3dz72    pripa-h3dzd7    pripa-h3epg7    pripa-h3ept4    pripa-h3ept8    pripa-h3ew78    pripa-h3ext9    pripa-h3f0j4    pripa-h3f919    pripa-h3f920    pripa-h3fcj7    pripa-h3fg45    pripa-h3fg46    pripa-h3fg51.2    pripa-h3fhh1    pripa-h3fhv6    pripa-h3fig0    pripa-h3fj25    pripa-h3fvb4    pripa-h3g1q9    pripa-h3g217    pripa-a0a0f5cf17    pripa-a0a0f5crg5    pripa-a0a0f5csq7    pripa-h3esz7    pripa-a0a0f5chi5    pripa-h3fh18    pripa-h3dzn5    pripa-h3ea81    pripa-h3ejs9    pripa-h3ejz6    pripa-h3ely7    pripa-h3f0w4    pripa-h3fg50    pripa-h3fg54    pripa-h3fsp0    pripa-h3fu59    pripa-h3fvb5    pripa-h3fvj9    pripa-h3g1r0    pripa-h3g1r3    pripa-a0a0f5c2j3    pripa-a0a0f5c3t4    pripa-a0a0f5cn29    pripa-a0a0f5crb3    pripa-a0a0f5d315

Citations formats

Dieterich C, Clifton SW, Schuster LN, Chinwalla A, Delehaunty K, Dinkelacker I, Fulton L, Fulton R, Godfrey J, Minx P, Mitreva M, Roeseler W, Tian H, Witte H, Yang SP, Wilson RK, Sommer RJ (2008)
The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism
Nat Genet 40 :1193

Dieterich C, Clifton SW, Schuster LN, Chinwalla A, Delehaunty K, Dinkelacker I, Fulton L, Fulton R, Godfrey J, Minx P, Mitreva M, Roeseler W, Tian H, Witte H, Yang SP, Wilson RK, Sommer RJ (2008)
Nat Genet 40 :1193