Mitreva M

References (10)

Title : The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia - Munoz_2015_PLoS.Genet_11_e1005493
Author(s) : Munoz JF , Gauthier GM , Desjardins CA , Gallo JE , Holder J , Sullivan TD , Marty AJ , Carmen JC , Chen Z , Ding L , Gujja S , Magrini V , Misas E , Mitreva M , Priest M , Saif S , Whiston EA , Young S , Zeng Q , Goldman WE , Mardis ER , Taylor JW , McEwen JG , Clay OK , Klein BS , Cuomo CA
Ref : PLoS Genet , 11 :e1005493 , 2015
Abstract : Three closely related thermally dimorphic pathogens are causal agents of major fungal diseases affecting humans in the Americas: blastomycosis, histoplasmosis and paracoccidioidomycosis. Here we report the genome sequence and analysis of four strains of the etiological agent of blastomycosis, Blastomyces, and two species of the related genus Emmonsia, typically pathogens of small mammals. Compared to related species, Blastomyces genomes are highly expanded, with long, often sharply demarcated tracts of low GC-content sequence. These GC-poor isochore-like regions are enriched for gypsy elements, are variable in total size between isolates, and are least expanded in the avirulent B. dermatitidis strain ER-3 as compared with the virulent B. gilchristii strain SLH14081. The lack of similar regions in related species suggests these isochore-like regions originated recently in the ancestor of the Blastomyces lineage. While gene content is highly conserved between Blastomyces and related fungi, we identified changes in copy number of genes potentially involved in host interaction, including proteases and characterized antigens. In addition, we studied gene expression changes of B. dermatitidis during the interaction of the infectious yeast form with macrophages and in a mouse model. Both experiments highlight a strong antioxidant defense response in Blastomyces, and upregulation of dioxygenases in vivo suggests that dioxide produced by antioxidants may be further utilized for amino acid metabolism. We identify a number of functional categories upregulated exclusively in vivo, such as secreted proteins, zinc acquisition proteins, and cysteine and tryptophan metabolism, which may include critical virulence factors missed before in in vitro studies. Across the dimorphic fungi, loss of certain zinc acquisition genes and differences in amino acid metabolism suggest unique adaptations of Blastomyces to its host environment. These results reveal the dynamics of genome evolution and of factors contributing to virulence in Blastomyces.
ESTHER : Munoz_2015_PLoS.Genet_11_e1005493
PubMedSearch : Munoz_2015_PLoS.Genet_11_e1005493
PubMedID: 26439490
Gene_locus related to this paper: ajedr-c5gqv9 , 9euro-a0a2b7ztc4 , 9euro-a0a2b7wr51 , blags-a0a179v0z0 , 9euro-a0a0h1bel0 , blags-a0a179udh1 , ajedr-kex1 , ajedr-cbpya

Title : Genome of the human hookworm Necator americanus - Tang_2014_Nat.Genet_46_261
Author(s) : Tang YT , Gao X , Rosa BA , Abubucker S , Hallsworth-Pepin K , Martin J , Tyagi R , Heizer E , Zhang X , Bhonagiri-Palsikar V , Minx P , Warren WC , Wang Q , Zhan B , Hotez PJ , Sternberg PW , Dougall A , Gaze ST , Mulvenna J , Sotillo J , Ranganathan S , Rabelo EM , Wilson RK , Felgner PL , Bethony J , Hawdon JM , Gasser RB , Loukas A , Mitreva M
Ref : Nat Genet , 46 :261 , 2014
Abstract : The hookworm Necator americanus is the predominant soil-transmitted human parasite. Adult worms feed on blood in the small intestine, causing iron-deficiency anemia, malnutrition, growth and development stunting in children, and severe morbidity and mortality during pregnancy in women. We report sequencing and assembly of the N. americanus genome (244 Mb, 19,151 genes). Characterization of this first hookworm genome sequence identified genes orchestrating the hookworm's invasion of the human host, genes involved in blood feeding and development, and genes encoding proteins that represent new potential drug targets against hookworms. N. americanus has undergone a considerable and unique expansion of immunomodulator proteins, some of which we highlight as potential treatments against inflammatory diseases. We also used a protein microarray to demonstrate a postgenomic application of the hookworm genome sequence. This genome provides an invaluable resource to boost ongoing efforts toward fundamental and applied postgenomic research, including the development of new methods to control hookworm and human immunological diseases.
ESTHER : Tang_2014_Nat.Genet_46_261
PubMedSearch : Tang_2014_Nat.Genet_46_261
PubMedID: 24441737
Gene_locus related to this paper: necam-w2tsu7

Title : Silencing of germline-expressed genes by DNA elimination in somatic cells - Wang_2012_Dev.Cell_23_1072
Author(s) : Wang J , Mitreva M , Berriman M , Thorne A , Magrini V , Koutsovoulos G , Kumar S , Blaxter ML , Davis RE
Ref : Dev Cell , 23 :1072 , 2012
Abstract : Chromatin diminution is the programmed elimination of specific DNA sequences during development. It occurs in diverse species, but the function(s) of diminution and the specificity of sequence loss remain largely unknown. Diminution in the nematode Ascaris suum occurs during early embryonic cleavages and leads to the loss of germline genome sequences and the formation of a distinct genome in somatic cells. We found that approximately 43 Mb ( approximately 13%) of genome sequence is eliminated in A. suum somatic cells, including approximately 12.7 Mb of unique sequence. The eliminated sequences and location of the DNA breaks are the same in all somatic lineages from a single individual and between different individuals. At least 685 genes are eliminated. These genes are preferentially expressed in the germline and during early embryogenesis. We propose that diminution is a mechanism of germline gene regulation that specifically removes a large number of genes involved in gametogenesis and early embryogenesis.
ESTHER : Wang_2012_Dev.Cell_23_1072
PubMedSearch : Wang_2012_Dev.Cell_23_1072
PubMedID: 23123092
Gene_locus related to this paper: ascsu-f1kr69 , ascsu-f1kxs8 , ascsu-f1ky57 , ascsu-f1kze8 , ascsu-f1kzv8 , ascsu-f1kzx8 , ascsu-f1l0a5 , ascsu-f1l0j3 , ascsu-f1l0s5 , ascsu-f1l1m9 , ascsu-f1l2e5 , ascsu-f1l3k2 , ascsu-f1l7s2 , ascsu-f1l145 , ascsu-u1mei8 , ascsu-u1ns34 , ascsu-u1nb30 , ascsu-f1kzg5 , ascsu-u1ntf1 , ascsu-u1nx87 , ascsu-f1l5f0 , ascsu-f1l6n2

Title : The draft genome of the parasitic nematode Trichinella spiralis - Mitreva_2011_Nat.Genet_43_228
Author(s) : Mitreva M , Jasmer DP , Zarlenga DS , Wang Z , Abubucker S , Martin J , Taylor CM , Yin Y , Fulton L , Minx P , Yang SP , Warren WC , Fulton RS , Bhonagiri V , Zhang X , Hallsworth-Pepin K , Clifton SW , McCarter JP , Appleton J , Mardis ER , Wilson RK
Ref : Nat Genet , 43 :228 , 2011
Abstract : Genome evolution studies for the phylum Nematoda have been limited by focusing on comparisons involving Caenorhabditis elegans. We report a draft genome sequence of Trichinella spiralis, a food-borne zoonotic parasite, which is the most common cause of human trichinellosis. This parasitic nematode is an extant member of a clade that diverged early in the evolution of the phylum, enabling identification of archetypical genes and molecular signatures exclusive to nematodes. We sequenced the 64-Mb nuclear genome, which is estimated to contain 15,808 protein-coding genes, at approximately 35-fold coverage using whole-genome shotgun and hierarchal map-assisted sequencing. Comparative genome analyses support intrachromosomal rearrangements across the phylum, disproportionate numbers of protein family deaths over births in parasitic compared to a non-parasitic nematode and a preponderance of gene-loss and -gain events in nematodes relative to Drosophila melanogaster. This genome sequence and the identified pan-phylum characteristics will contribute to genome evolution studies of Nematoda as well as strategies to combat global parasites of humans, food animals and crops.
ESTHER : Mitreva_2011_Nat.Genet_43_228
PubMedSearch : Mitreva_2011_Nat.Genet_43_228
PubMedID: 21336279
Gene_locus related to this paper: trisp-ACHE1 , trisp-e5ryh1 , trisp-e5s2p1 , trisp-e5s3s1 , trisp-e5s5l6 , trisp-e5s7y8 , trisp-e5s8m6 , trisp-e5s9j3 , trisp-e5s254 , trisp-e5s773 , trisp-e5sav1 , trisp-e5sbp4 , trisp-e5sgg4 , trisp-e5sgu8 , trisp-e5snw0 , trisp-e5sr61 , trisp-e5ss42 , trisp-e5sgh2 , 9bila-a0a0v0tgw4.1 , 9bila-a0a0v0tws5

Title : Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles - Wang_2011_Genome.Res_21_1462
Author(s) : Wang J , Czech B , Crunk A , Wallace A , Mitreva M , Hannon GJ , Davis RE
Ref : Genome Res , 21 :1462 , 2011
Abstract : Eukaryotic cells express several classes of small RNAs that regulate gene expression and ensure genome maintenance. Endogenous siRNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs) mainly control gene and transposon expression in the germline, while microRNAs (miRNAs) generally function in post-transcriptional gene silencing in both somatic and germline cells. To provide an evolutionary and developmental perspective on small RNA pathways in nematodes, we identified and characterized known and novel small RNA classes through gametogenesis and embryo development in the parasitic nematode Ascaris suum and compared them with known small RNAs of Caenorhabditis elegans. piRNAs, Piwi-clade Argonautes, and other proteins associated with the piRNA pathway have been lost in Ascaris. miRNAs are synthesized immediately after fertilization in utero, before pronuclear fusion, and before the first cleavage of the zygote. This is the earliest expression of small RNAs ever described at a developmental stage long thought to be transcriptionally quiescent. A comparison of the two classes of Ascaris endo-siRNAs, 22G-RNAs and 26G-RNAs, to those in C. elegans, suggests great diversification and plasticity in the use of small RNA pathways during spermatogenesis in different nematodes. Our data reveal conserved characteristics of nematode small RNAs as well as features unique to Ascaris that illustrate significant flexibility in the use of small RNAs pathways, some of which are likely an adaptation to Ascaris' life cycle and parasitism. The transcriptome assembly has been submitted to NCBI Transcriptome Shotgun Assembly Sequence Database(http:\/\/ under accession numbers JI163767-JI182837 and JI210738-JI257410.
ESTHER : Wang_2011_Genome.Res_21_1462
PubMedSearch : Wang_2011_Genome.Res_21_1462
PubMedID: 21685128
Gene_locus related to this paper: ascsu-f1kpy0.2 , ascsu-f1kpy0.3 , ascsu-f1kpy0.4 , ascsu-f1kr69 , ascsu-f1ktc3 , ascsu-f1ktc5 , ascsu-f1ktw1.1 , ascsu-f1ktw1.2 , ascsu-f1ktx4 , ascsu-f1kwb2 , ascsu-f1kwb5 , ascsu-f1kwf0 , ascsu-f1kxs8 , ascsu-f1ky57 , ascsu-f1kz22 , ascsu-f1kze8 , ascsu-f1kzv8 , ascsu-f1kzx8 , ascsu-f1l0a5 , ascsu-f1l0j3 , ascsu-f1l0s4 , ascsu-f1l0s5 , ascsu-f1l1k4 , ascsu-f1l1m9 , ascsu-f1l1p8 , ascsu-f1l2e5 , ascsu-f1l2m0 , ascsu-f1l3k2 , ascsu-f1l5n5 , ascsu-f1l6s4 , ascsu-f1l7s2 , ascsu-f1l108 , ascsu-f1l145 , ascsu-f1la00 , ascsu-f1lav9 , ascsu-u1mei8 , ascsu-u1ns34 , ascsu-u1nb30 , ascsu-f1kzg5 , ascsu-f1l726 , ascsu-u1ntf1 , ascsu-u1nx87 , ascsu-f1l5f0 , ascsu-f1l6n2

Title : A catalog of reference genomes from the human microbiome - Nelson_2010_Science_328_994
Author(s) : Nelson KE , Weinstock GM , Highlander SK , Worley KC , Creasy HH , Wortman JR , Rusch DB , Mitreva M , Sodergren E , Chinwalla AT , Feldgarden M , Gevers D , Haas BJ , Madupu R , Ward DV , Birren BW , Gibbs RA , Methe B , Petrosino JF , Strausberg RL , Sutton GG , White OR , Wilson RK , Durkin S , Giglio MG , Gujja S , Howarth C , Kodira CD , Kyrpides N , Mehta T , Muzny DM , Pearson M , Pepin K , Pati A , Qin X , Yandava C , Zeng Q , Zhang L , Berlin AM , Chen L , Hepburn TA , Johnson J , McCorrison J , Miller J , Minx P , Nusbaum C , Russ C , Sykes SM , Tomlinson CM , Young S , Warren WC , Badger J , Crabtree J , Markowitz VM , Orvis J , Cree A , Ferriera S , Fulton LL , Fulton RS , Gillis M , Hemphill LD , Joshi V , Kovar C , Torralba M , Wetterstrand KA , Abouellleil A , Wollam AM , Buhay CJ , Ding Y , Dugan S , Fitzgerald MG , Holder M , Hostetler J , Clifton SW , Allen-Vercoe E , Earl AM , Farmer CN , Liolios K , Surette MG , Xu Q , Pohl C , Wilczek-Boney K , Zhu D
Ref : Science , 328 :994 , 2010
Abstract : The human microbiome refers to the community of microorganisms, including prokaryotes, viruses, and microbial eukaryotes, that populate the human body. The National Institutes of Health launched an initiative that focuses on describing the diversity of microbial species that are associated with health and disease. The first phase of this initiative includes the sequencing of hundreds of microbial reference genomes, coupled to metagenomic sequencing from multiple body sites. Here we present results from an initial reference genome sequencing of 178 microbial genomes. From 547,968 predicted polypeptides that correspond to the gene complement of these strains, previously unidentified ("novel") polypeptides that had both unmasked sequence length greater than 100 amino acids and no BLASTP match to any nonreference entry in the nonredundant subset were defined. This analysis resulted in a set of 30,867 polypeptides, of which 29,987 (approximately 97%) were unique. In addition, this set of microbial genomes allows for approximately 40% of random sequences from the microbiome of the gastrointestinal tract to be associated with organisms based on the match criteria used. Insights into pan-genome analysis suggest that we are still far from saturating microbial species genetic data sets. In addition, the associated metrics and standards used by our group for quality assurance are presented.
ESTHER : Nelson_2010_Science_328_994
PubMedSearch : Nelson_2010_Science_328_994
PubMedID: 20489017
Gene_locus related to this paper: strp2-q04l35 , strpn-AXE1 , strpn-pepx

Title : Transcripts analysis of the entomopathogenic nematode Steinernema carpocapsae induced in vitro with insect haemolymph - Hao_2010_Mol.Biochem.Parasitol_169_79
Author(s) : Hao YJ , Montiel R , Abubucker S , Mitreva M , Simoes N
Ref : Molecular & Biochemical Parasitology , 169 :79 , 2010
Abstract : Steinernema carpocapsae is an insect parasitic nematode widely used in pest control programs. The efficacy of this nematode in controlling insects has been found to be related to the pathogenicity of the infective stage. In order to study the parasitic mechanisms exhibited by this parasite, a cDNA library of the induced S. carpocapsae parasitic phase was generated. A total of 2500 clones were sequenced and 2180 high-quality ESTs were obtained from this library. Cluster analysis generated a total of 1592 unique sequences including 1393 singletons. About 63% of the unique sequences had significant hits (e<=1e-05) to the non-redundant protein database. The remaining sequences most likely represent putative novel protein coding genes. Comparative analysis identified 377 homologs in C. elegans, 431 in C. briggsae and 75 in other nematodes. Classification of the predicted proteins revealed involvement in diverse cellular, metabolic and extracellular functions. One hundred and nineteen clusters were predicted to encode putative secreted proteins such as proteases, proteases inhibitors, lectins, saposin-like proteins, acetylcholinesterase, anti-oxidants, and heat-shock proteins, which can possibly have host interactions. This dataset provides a basis for genomic studies towards a better understanding of the events that occur in the parasitic process of this entomopathogenic nematode, including invasion of the insect haemocoelium, adaptations to insect innate immunity and stress responses, and production of virulence factors. The identification of key genes in the parasitic process provides useful tools for the improvement of S. carpocapsae as a biological agent.
ESTHER : Hao_2010_Mol.Biochem.Parasitol_169_79
PubMedSearch : Hao_2010_Mol.Biochem.Parasitol_169_79
PubMedID: 19836423

Title : Genome analysis of the platypus reveals unique signatures of evolution - Warren_2008_Nature_453_175
Author(s) : Warren WC , Hillier LW , Marshall Graves JA , Birney E , Ponting CP , Grutzner F , Belov K , Miller W , Clarke L , Chinwalla AT , Yang SP , Heger A , Locke DP , Miethke P , Waters PD , Veyrunes F , Fulton L , Fulton B , Graves T , Wallis J , Puente XS , Lopez-Otin C , Ordonez GR , Eichler EE , Chen L , Cheng Z , Deakin JE , Alsop A , Thompson K , Kirby P , Papenfuss AT , Wakefield MJ , Olender T , Lancet D , Huttley GA , Smit AF , Pask A , Temple-Smith P , Batzer MA , Walker JA , Konkel MK , Harris RS , Whittington CM , Wong ES , Gemmell NJ , Buschiazzo E , Vargas Jentzsch IM , Merkel A , Schmitz J , Zemann A , Churakov G , Kriegs JO , Brosius J , Murchison EP , Sachidanandam R , Smith C , Hannon GJ , Tsend-Ayush E , McMillan D , Attenborough R , Rens W , Ferguson-Smith M , Lefevre CM , Sharp JA , Nicholas KR , Ray DA , Kube M , Reinhardt R , Pringle TH , Taylor J , Jones RC , Nixon B , Dacheux JL , Niwa H , Sekita Y , Huang X , Stark A , Kheradpour P , Kellis M , Flicek P , Chen Y , Webber C , Hardison R , Nelson J , Hallsworth-Pepin K , Delehaunty K , Markovic C , Minx P , Feng Y , Kremitzki C , Mitreva M , Glasscock J , Wylie T , Wohldmann P , Thiru P , Nhan MN , Pohl CS , Smith SM , Hou S , Nefedov M , de Jong PJ , Renfree MB , Mardis ER , Wilson RK
Ref : Nature , 453 :175 , 2008
Abstract : We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus biology. Expansions of protein, non-protein-coding RNA and microRNA families, as well as repeat elements, are identified. Sequencing of this genome now provides a valuable resource for deep mammalian comparative analyses, as well as for monotreme biology and conservation.
ESTHER : Warren_2008_Nature_453_175
PubMedSearch : Warren_2008_Nature_453_175
PubMedID: 18464734
Gene_locus related to this paper: ornan-f6s0q0 , ornan-f6ty74 , ornan-f6u2k2 , ornan-f6uve1 , ornan-f6vpb6 , ornan-f6ybp3 , ornan-f7bgu8 , ornan-f7ct41 , ornan-f7cza1 , ornan-f7ejp8 , ornan-f7exu1 , ornan-f7f392 , ornan-f7f9y6 , ornan-f6ve87 , ornan-f7f1d9 , ornan-f6z3l1 , ornan-f6r3f9 , ornan-f6r3g8 , ornan-f6vs71 , ornan-f7g4v8

Title : The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism - Dieterich_2008_Nat.Genet_40_1193
Author(s) : Dieterich C , Clifton SW , Schuster LN , Chinwalla A , Delehaunty K , Dinkelacker I , Fulton L , Fulton R , Godfrey J , Minx P , Mitreva M , Roeseler W , Tian H , Witte H , Yang SP , Wilson RK , Sommer RJ
Ref : Nat Genet , 40 :1193 , 2008
Abstract : Here we present a draft genome sequence of the nematode Pristionchus pacificus, a species that is associated with beetles and is used as a model system in evolutionary biology. With 169 Mb and 23,500 predicted protein-coding genes, the P. pacificus genome is larger than those of Caenorhabditis elegans and the human parasite Brugia malayi. Compared to C. elegans, the P. pacificus genome has more genes encoding cytochrome P450 enzymes, glucosyltransferases, sulfotransferases and ABC transporters, many of which were experimentally validated. The P. pacificus genome contains genes encoding cellulase and diapausin, and cellulase activity is found in P. pacificus secretions, indicating that cellulases can be found in nematodes beyond plant parasites. The relatively higher number of detoxification and degradation enzymes in P. pacificus is consistent with its necromenic lifestyle and might represent a preadaptation for parasitism. Thus, comparative genomics analysis of three ecologically distinct nematodes offers a unique opportunity to investigate the association between genome structure and lifestyle.
ESTHER : Dieterich_2008_Nat.Genet_40_1193
PubMedSearch : Dieterich_2008_Nat.Genet_40_1193
PubMedID: 18806794
Gene_locus related to this paper: pripa-h3dz72 , pripa-h3dzd7 , pripa-h3epg7 , pripa-h3ept4 , pripa-h3ept8 , pripa-h3ew78 , pripa-h3ext9 , pripa-h3f0j4 , pripa-h3f919 , pripa-h3f920 , pripa-h3fcj7 , pripa-h3fg45 , pripa-h3fg46 , pripa-h3fg51.2 , pripa-h3fhh1 , pripa-h3fhv6 , pripa-h3fig0 , pripa-h3fj25 , pripa-h3fvb4 , pripa-h3g1q9 , pripa-h3g217 , pripa-a0a0f5cf17 , pripa-a0a0f5crg5 , pripa-a0a0f5csq7 , pripa-h3esz7 , pripa-a0a0f5chi5 , pripa-h3fh18 , pripa-h3dzn5

Title : Draft genome of the filarial nematode parasite Brugia malayi - Ghedin_2007_Science_317_1756
Author(s) : Ghedin E , Wang S , Spiro D , Caler E , Zhao Q , Crabtree J , Allen JE , Delcher AL , Guiliano DB , Miranda-Saavedra D , Angiuoli SV , Creasy T , Amedeo P , Haas B , El-Sayed NM , Wortman JR , Feldblyum T , Tallon L , Schatz M , Shumway M , Koo H , Salzberg SL , Schobel S , Pertea M , Pop M , White O , Barton GJ , Carlow CK , Crawford MJ , Daub J , Dimmic MW , Estes CF , Foster JM , Ganatra M , Gregory WF , Johnson NM , Jin J , Komuniecki R , Korf I , Kumar S , Laney S , Li BW , Li W , Lindblom TH , Lustigman S , Ma D , Maina CV , Martin DM , McCarter JP , McReynolds L , Mitreva M , Nutman TB , Parkinson J , Peregrin-Alvarez JM , Poole C , Ren Q , Saunders L , Sluder AE , Smith K , Stanke M , Unnasch TR , Ware J , Wei AD , Weil G , Williams DJ , Zhang Y , Williams SA , Fraser-Liggett C , Slatko B , Blaxter ML , Scott AL
Ref : Science , 317 :1756 , 2007
Abstract : Parasitic nematodes that cause elephantiasis and river blindness threaten hundreds of millions of people in the developing world. We have sequenced the approximately 90 megabase (Mb) genome of the human filarial parasite Brugia malayi and predict approximately 11,500 protein coding genes in 71 Mb of robustly assembled sequence. Comparative analysis with the free-living, model nematode Caenorhabditis elegans revealed that, despite these genes having maintained little conservation of local synteny during approximately 350 million years of evolution, they largely remain in linkage on chromosomal units. More than 100 conserved operons were identified. Analysis of the predicted proteome provides evidence for adaptations of B. malayi to niches in its human and vector hosts and insights into the molecular basis of a mutualistic relationship with its Wolbachia endosymbiont. These findings offer a foundation for rational drug design.
ESTHER : Ghedin_2007_Science_317_1756
PubMedSearch : Ghedin_2007_Science_317_1756
PubMedID: 17885136
Gene_locus related to this paper: bruma-a8ndk6 , bruma-a8njt8 , bruma-a8nl88 , bruma-a8npi4 , bruma-a8npi6 , bruma-a8p6g9 , bruma-a8pah3 , bruma-a8pc38 , bruma-a8pek5 , bruma-a8piq4 , bruma-a8pnw8 , bruma-a8psu4 , bruma-a8pte1 , bruma-a8q606 , bruma-a8q632 , bruma-a8q937 , bruma-a8qav5 , bruma-a8qbd9 , bruma-a8qgj6 , bruma-a8qh78 , bruma-a8q143 , bruma-a0a024mej5 , bruma-a0a0k0jju9 , bruma-a0a0i9n517