Prozorovskii_1994_Eksp.Klin.Farmakol_57_13

Reference

Title : [Aminostigmine as a cholinesterase inhibitor and as an agent for treating poisonings by cholinergic blockers]. [Russian] - Prozorovskii_1994_Eksp.Klin.Farmakol_57_13
Author(s) : Prozorovskii VB , Livanov GA , Velikova VD , Afanas'ev VV , Pavlova LV
Ref : Eksperimentalnaia i Klinicheskaia Farmakologiia , 57 :13 , 1994
Abstract : Experiments on non-inbred albino mice have demonstrated that aminostigmine is an active reversible centrally active cholinesterase inhibitor close to the properties of physostigmine, but greatly superior to it in its action duration. Clinical examinations of healthy volunteers and patients have shown that aminostigmine-induced inhibition of cholinesterase activity persists 6 hours. The agent have been found to be more highly effective in treating cholin blocker-induced intoxications than galanthamine, which manifests itself in its greater stability of the therapeutical effect achieved and in its higher ability to prevent cardiovascular events occurring in intoxication.
ESTHER : Prozorovskii_1994_Eksp.Klin.Farmakol_57_13
PubMedSearch : Prozorovskii_1994_Eksp.Klin.Farmakol_57_13
PubMedID: 7696893

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Citations formats

Prozorovskii VB, Livanov GA, Velikova VD, Afanas'ev VV, Pavlova LV (1994)
[Aminostigmine as a cholinesterase inhibitor and as an agent for treating poisonings by cholinergic blockers]. [Russian]
Eksperimentalnaia i Klinicheskaia Farmakologiia 57 :13

Prozorovskii VB, Livanov GA, Velikova VD, Afanas'ev VV, Pavlova LV (1994)
Eksperimentalnaia i Klinicheskaia Farmakologiia 57 :13