Paper Report for: Aury_2006_Nature_444_171 Reference
Title: Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia
Aury JM , Jaillon O , Duret L , Noel B , Jubin C , Porcel BM , Segurens B , Daubin V , Anthouard V and Wincker P <33 more author(s)>
Aury JM , Jaillon O , Duret L , Noel B , Jubin C , Porcel BM , Segurens B , Daubin V , Anthouard V , Aiach N , Arnaiz O , Billaut A , Beisson J , Blanc I , Bouhouche K , Camara F , Duharcourt S , Guigo R , Gogendeau D , Katinka M , Keller AM , Kissmehl R , Klotz C , Koll F , Le Mouel A , Lepere G , Malinsky S , Nowacki M , Nowak JK , Plattner H , Poulain J , Ruiz F , Serrano V , Zagulski M , Dessen P , Betermier M , Weissenbach J , Scarpelli C , Schachter V , Sperling L , Meyer E , Cohen J , Wincker P (- 33)
Ref: Nature,
444 :171, 2006 :
PubMed Abstract PubMedSearch: Aury 2006 Nature 444 171 PubMedID: 17086204 Gene_locus related to this paper: parte-a0bds8 ,
parte-a0bga5 ,
parte-a0bnp2 ,
parte-a0bnt1 ,
parte-a0bpr4 ,
parte-a0btv5 ,
parte-a0byt1 ,
parte-a0bz94 ,
parte-a0c0b8 ,
parte-a0c0q4 ,
parte-a0c1z8 ,
parte-a0c3e0 ,
parte-a0c9f4 ,
parte-a0c962 ,
parte-a0cb90 ,
parte-a0cck1 ,
parte-a0cj40 ,
parte-a0cq13 ,
parte-a0cqw8 ,
parte-a0crq3 ,
parte-a0cu52 ,
parte-a0cur9 ,
parte-a0cxu4 ,
parte-a0cyf3 ,
parte-a0czs5 ,
parte-a0d1l8 ,
parte-a0d9i7 ,
parte-a0d589 ,
parte-a0de29 ,
parte-a0dem3 ,
parte-a0dg79 ,
parte-a0diq2 ,
parte-a0dk36 ,
parte-a0dkh0 ,
parte-a0dld4 ,
parte-a0dnw2 ,
parte-a0drp9 ,
parte-a0drx0 ,
parte-a0duj9 ,
parte-a0dvl0 ,
parte-a0dwm9 ,
parte-a0dy72 ,
parte-a0dz74 ,
parte-a0e0g8 ,
parte-a0e0z4 ,
parte-a0e1p0 ,
parte-a0e4m9 ,
parte-a0e8v9 ,
parte-a0e9r1 ,
parte-a0e581 ,
parte-a0ecy9 ,
parte-a0ecz4 ,
parte-a0ef67 ,
parte-a0d7k3 Abstract
The duplication of entire genomes has long been recognized as having great potential for evolutionary novelties, but the mechanisms underlying their resolution through gene loss are poorly understood. Here we show that in the unicellular eukaryote Paramecium tetraurelia, a ciliate, most of the nearly 40,000 genes arose through at least three successive whole-genome duplications. Phylogenetic analysis indicates that the most recent duplication coincides with an explosion of speciation events that gave rise to the P. aurelia complex of 15 sibling species. We observed that gene loss occurs over a long timescale, not as an initial massive event. Genes from the same metabolic pathway or protein complex have common patterns of gene loss, and highly expressed genes are over-retained after all duplications. The conclusion of this analysis is that many genes are maintained after whole-genome duplication not because of functional innovation but because of gene dosage constraints.
        
Related information
Gene_Locus | parte-a0bds8 , parte-a0bga5 , parte-a0bnp2 , parte-a0bnt1 , parte-a0bpr4 , parte-a0btv5 , parte-a0byt1 , parte-a0bz94 , parte-a0c0b8 , parte-a0c0q4 , parte-a0c1z8 , parte-a0c3e0 , parte-a0c9f4 , parte-a0c962 , parte-a0cb90 , parte-a0cck1 , parte-a0cj40 , parte-a0cq13 , parte-a0cqw8 , parte-a0crq3 , parte-a0cu52 , parte-a0cur9 , parte-a0cxu4 , parte-a0cyf3 , parte-a0czs5 , parte-a0d1l8 , parte-a0d9i7 , parte-a0d589 , parte-a0de29 , parte-a0dem3 , parte-a0dg79 , parte-a0diq2 , parte-a0dk36 , parte-a0dkh0 , parte-a0dld4 , parte-a0dnw2 , parte-a0drp9 , parte-a0drx0 , parte-a0duj9 , parte-a0dvl0 , parte-a0dwm9 , parte-a0dy72 , parte-a0dz74 , parte-a0e0g8 , parte-a0e0z4 , parte-a0e1p0 , parte-a0e4m9 , parte-a0e8v9 , parte-a0e9r1 , parte-a0e581 , parte-a0ecy9 , parte-a0ecz4 , parte-a0ef67 , parte-a0d7k3
Citations formats
Aury JM, Jaillon O, Duret L, Noel B, Jubin C, Porcel BM, Segurens B, Daubin V, Anthouard V, Aiach N, Arnaiz O, Billaut A, Beisson J, Blanc I, Bouhouche K, Camara F, Duharcourt S, Guigo R, Gogendeau D, Katinka M, Keller AM, Kissmehl R, Klotz C, Koll F, Le Mouel A, Lepere G, Malinsky S, Nowacki M, Nowak JK, Plattner H, Poulain J, Ruiz F, Serrano V, Zagulski M, Dessen P, Betermier M, Weissenbach J, Scarpelli C, Schachter V, Sperling L, Meyer E, Cohen J, Wincker P (2006) Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraureliaNature 444 : 171-8 Aury JM, Jaillon O, Duret L, Noel B, Jubin C, Porcel BM, Segurens B, Daubin V, Anthouard V, Aiach N, Arnaiz O, Billaut A, Beisson J, Blanc I, Bouhouche K, Camara F, Duharcourt S, Guigo R, Gogendeau D, Katinka M, Keller AM, Kissmehl R, Klotz C, Koll F, Le Mouel A, Lepere G, Malinsky S, Nowacki M, Nowak JK, Plattner H, Poulain J, Ruiz F, Serrano V, Zagulski M, Dessen P, Betermier M, Weissenbach J, Scarpelli C, Schachter V, Sperling L, Meyer E, Cohen J, Wincker P (2006) Nature 444 : 171-8