Amodiaquine

General

Type : non-oxime, Quinoline

Chemical_Nomenclature : 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol

Canonical SMILES : CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O

InChI : InChI=1S\/C20H22ClN3O\/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19\/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)

InChIKey : OVCDSSHSILBFBN-UHFFFAOYSA-N

Other name(s) : ADQ  ||  Amodiaquin  ||  Camoquine  ||  Flavoquine  ||  Camoquin  ||  Camochin


MW : 355.86

Formula : C20H22ClN3O

CAS_number : 86-42-0

PubChem : 2165

UniChem : OVCDSSHSILBFBN-UHFFFAOYSA-N

Target

Structure : No structure

Families : ACHE

References (2)

Title : New therapeutic approaches and novel alternatives for organophosphate toxicity - Katz_2018_Toxicol.Lett_291_1
Author(s) : Katz FS , Pecic S , Schneider L , Zhu Z , Hastings A , Luzac M , MacDonald J , Landry DW , Stojanovic MN
Ref : Toxicol Lett , 291 :1 , 2018
Abstract :
PubMedSearch : Katz_2018_Toxicol.Lett_291_1
PubMedID: 29614332

Title : Kinetic analysis of interactions of amodiaquine with human cholinesterases and organophosphorus compounds - Bierwisch_2016_Toxicol.Lett_246_49
Author(s) : Bierwisch A , Wille T , Thiermann H , Worek F
Ref : Toxicol Lett , 246 :49 , 2016
Abstract :
PubMedSearch : Bierwisch_2016_Toxicol.Lett_246_49
PubMedID: 26851641