BI-6
General
Type : Oxime, Bispyridinium, Carboxamide
Chemical_Nomenclature : 1-[4-[2-(nitrosomethyl)pyridin-1-ium-1-yl]but-2-enyl]pyridin-1-ium-4-carboxamide
Canonical SMILES : C1=CC=[N+](C(=C1)CN=O)CC=CC[N+]2=CC=C(C=C2)C(=O)N
InChI : InChI=1S\/C16H17N4O2\/c17-16(21)14-6-11-19(12-7-14)8-3-4-10-20-9-2-1-5-15(20)13-18-22\/h1-7,9,11-12H,8,10,13H2,(H-,17,21)\/q+1\/p+1
InChIKey : BJTLWOFUMXTEKF-UHFFFAOYSA-O
Other name(s) : 1-2-hydroxyiminomethylpyridinium-4 carbamoylpyridinium-2-butene dibromide
MW : 298.33
Formula : C16H18N4O2
CAS_number :
PubChem : 91218446
UniChem : BJTLWOFUMXTEKF-UHFFFAOYSA-O
Target
Structure : No structure
Families : No family
References (10)
| Title : Molecular modeling and in vitro reactivation study between the oxime BI-6 and acetylcholinesterase inhibited by different nerve agents - Giacoppo_2015_J.Biomol.Struct.Dyn_33_2048 |
| Author(s) : Giacoppo JO , Franca TCC , Kuca K , da Cunha EFF , Abagyan R , Mancini DT , Ramalho TC |
| Ref : J Biomol Struct Dyn , 33 :2048 , 2015 |
| Abstract : |
| PubMedSearch : Giacoppo_2015_J.Biomol.Struct.Dyn_33_2048 |
| PubMedID: 25407587 |
| Title : Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon - Petroianu_2006_J.Appl.Toxicol_26_64 |
| Author(s) : Petroianu GA , Arafat K , Kuca K , Kassa J |
| Ref : J Appl Toxicol , 26 :64 , 2006 |
| Abstract : |
| PubMedSearch : Petroianu_2006_J.Appl.Toxicol_26_64 |
| PubMedID: 16193529 |
| Title : Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: survival in rats exposed to the organophosphate paraoxon - Petroianu_2006_J.Appl.Toxicol_26_262 |
| Author(s) : Petroianu GA , Nurulain SM , Nagelkerke N , Al-Sultan MA , Kuca K , Kassa J |
| Ref : J Appl Toxicol , 26 :262 , 2006 |
| Abstract : |
| PubMedSearch : Petroianu_2006_J.Appl.Toxicol_26_262 |
| PubMedID: 16583462 |
| Title : In vitro potency of H oximes (HI-6, HLo-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase - Kuca_2006_J.Toxicol.Environ.Health.A_69_1431 |
| Author(s) : Kuca K , Cabal J , Kassa J , Jun D , Hrabinova M |
| Ref : J Toxicol Environ Health A , 69 :1431 , 2006 |
| Abstract : |
| PubMedSearch : Kuca_2006_J.Toxicol.Environ.Health.A_69_1431 |
| PubMedID: 16766478 |
| Title : [Comparison of the reactivating effect of BI-6, a new asymmetrical bispyridinium oxime, with oxime HI-6 and obidoxime on soman-inhibited acetylcholinesterase in the diaphragm and various parts of the brain in rats] - Kassa_1999_Cas.Lek.Cesk_138_532 |
| Author(s) : Kassa J , Bajgar J |
| Ref : Casopis Lekaru Ceskych , 138 :532 , 1999 |
| Abstract : |
| PubMedSearch : Kassa_1999_Cas.Lek.Cesk_138_532 |
| PubMedID: 10566233 |
| Title : [Comparison of the effects of BI-6, a new asymmetric bipyridine oxime, with HI-6 oxime and obidoxime in combination with atropine on soman and fosdrine toxicity in mice] - Kassa_1999_Ceska.Slov.Farm_48_44 |
| Author(s) : Kassa J |
| Ref : Ceska a Slovenska Farmacie , 48 :44 , 1999 |
| Abstract : |
| PubMedSearch : Kassa_1999_Ceska.Slov.Farm_48_44 |
| PubMedID: 10376416 |
| Title : A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with presently used oximes and H oximes against sarin by in vitro and in vivo methods - Kassa_1999_Hum.Toxicol_18_560 |
| Author(s) : Kassa J , Cabal J |
| Ref : Hum Toxicol , 18 :560 , 1999 |
| Abstract : |
| PubMedSearch : Kassa_1999_Hum.Toxicol_18_560 |
| PubMedID: 10523870 |
| Title : A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with currently available oximes and H oximes against soman by in vitro and in vivo methods - Kassa_1999_Toxicology_132_111 |
| Author(s) : Kassa J , Cabal J |
| Ref : Toxicology , 132 :111 , 1999 |
| Abstract : |
| PubMedSearch : Kassa_1999_Toxicology_132_111 |
| PubMedID: 10433374 |
| Title : A comparison of the therapeutic efficacy of conventional and modern oximes against supralethal doses of highly toxic organophosphates in mice - Kassa_1998_Acta.Medica_41_19 |
| Author(s) : Kassa J |
| Ref : Acta Medica , 41 :19 , 1998 |
| Abstract : |
| PubMedSearch : Kassa_1998_Acta.Medica_41_19 |
| PubMedID: 9588068 |
| Title : A comparison of the efficacy of new asymmetric bispyridinium oxime BI-6 with other oximes (obidoxime, HI-6) against soman in rats - Kassa_1998_Hum.Exp.Toxicol_17_331 |
| Author(s) : Kassa J |
| Ref : Hum Exp Toxicol , 17 :331 , 1998 |
| Abstract : |
| PubMedSearch : Kassa_1998_Hum.Exp.Toxicol_17_331 |
| PubMedID: 9688357 |