1EK2

Name : Mouse epoxyde hydrolase complexed with Cdu inhibitor

Revelation date : 31-May-2000

Family : Epoxide_hydrolase

Gene_locus : mouse-hyes

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Only the C-terminal part (from aa 226)of the protein has the alpha\/beta hydrolase fold. The N terminal part is alpha\/beta Rossmann-fold related to L-2-Haloacid dehalogenase, HAD

Ligand : Inhibitor CDU Ligand in structure: Ligplot

References (1)

Title : Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase - Argiriadi_1999_Proc.Natl.Acad.Sci.U.S.A_96_10637
Author(s) : Argiriadi MA , Morisseau C , Hammock BD , Christianson DW
Ref : Proceedings of the National Academy of Sciences of the United States of America , 96 :10637 , 1999
Abstract :
PubMedSearch : Argiriadi_1999_Proc.Natl.Acad.Sci.U.S.A_96_10637
PubMedID: 10485878
Gene_locus related to this paper: mouse-hyes

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 1EK2 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 1EK2 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 1EK2 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 1EK2 3D, interactive encyclopedia of proteins - PROTEOPEDIA server