2P8S
Name : Human dipeptidyl peptidase IV\/CD26 in complex with a cyclohexalamine inhibitor
Revelation date : 22-May-2007
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Scapin, G., Biftu, T.
Ligand : Inhibitor CHEMBL233360 Ligand in structure: Ligplot
References (1)
| Title : Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin - Biftu_2007_Bioorg.Med.Chem.Lett_17_3384 |
| Author(s) : Biftu T , Scapin G , Singh S , Feng D , Becker JW , Eiermann G , He H , Lyons K , Patel S , Petrov A , Sinha-Roy R , Zhang B , Wu J , Zhang X , Doss GA , Thornberry NA , Weber AE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :3384 , 2007 |
| Abstract : |
| PubMedSearch : Biftu_2007_Bioorg.Med.Chem.Lett_17_3384 |
| PubMedID: 17433672 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 2P8S Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 2P8S Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 2P8S Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 2P8S 3D, interactive encyclopedia of proteins - PROTEOPEDIA server