Lyons K

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Gene_locus related to this paper: human-DPP4

Title : Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines - Kim_2008_J.Med.Chem_51_589
Author(s) : Kim D , Kowalchick JE , Brockunier LL , Parmee ER , Eiermann GJ , Fisher MH , He H , Leiting B , Lyons K , Scapin G , Patel SB , Petrov A , Pryor KD , Roy RS , Wu JK , Zhang X , Wyvratt MJ , Zhang BB , Zhu L , Thornberry NA , Weber AE
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Title : (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)- 1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Biftu_2007_Bioorg.Med.Chem.Lett_17_49
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Gene_locus related to this paper: human-DPP4

Title : Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin - Biftu_2007_Bioorg.Med.Chem.Lett_17_3384
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Title : Optimization of 1,4-diazepan-2-one containing dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes - Liang_2007_Bioorg.Med.Chem.Lett_17_1903
Author(s) : Liang GB , Qian X , Feng D , Biftu T , Eiermann G , He H , Leiting B , Lyons K , Petrov A , Sinha-Roy R , Zhang B , Wu J , Zhang X , Thornberry NA , Weber AE
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Gene_locus related to this paper: human-DPP4

Title : (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)- yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Kim_2005_J.Med.Chem_48_141
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Gene_locus related to this paper: human-DPP4

Title : 4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors - Parmee_2004_Bioorg.Med.Chem.Lett_14_43
Author(s) : Parmee ER , He J , Mastracchio A , Edmondson SD , Colwell L , Eiermann G , Feeney WP , Habulihaz B , He H , Kilburn R , Leiting B , Lyons K , Marsilio F , Patel RA , Petrov A , Di Salvo J , Wu JK , Thornberry NA , Weber AE
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