Name : Dipepdyl peptidase IV in complex with inhibitor PZF

Revelation date : 29-Jul-2008

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, Liu S, McClure LD, McPherson RK, Olson TV, Orena SJ, Parker JC, Rocke BN, Soeller WC, Soglia CB, Treadway JL, Vanvolkenburg MA, Zhao Z, Cox ED

Ligand :

References (1)

Title : (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization - Wright_2007_Bioorg.Med.Chem.Lett_17_5638
Author(s) : Wright SW , Ammirati MJ , Andrews KM , Brodeur AM , Danley DE , Doran SD , Lillquist JS , Liu S , McClure LD , McPherson RK , Olson TV , Orena SJ , Parker JC , Rocke BN , Soeller WC , Soglia CB , Treadway JL , VanVolkenburg MA , Zhao Z , Cox ED
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :5638 , 2007
PubMedID: 17822893
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 2QJR Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 2QJR Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 2QJR Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 2QJR 3D, interactive encyclopedia of proteins - PROTEOPEDIA server