Name : Crystal Structure of Dipeptidyl Peptidase IV in complex with TAK-322

Revelation date : 16-Feb-2010

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Zhang, Zhiyuan, Wallace, Michael B., Feng, Jun, Stafford, Jeffrey A., Kaldor, Stephen W., Lihong, Shi, Skene, Robert J., Aertgeerts, Kathleen, Lee, Bumsup, Jennings, Andy, Xu, Rongda, Kassel, Daniel, Webb, David R., Gwaltney, Stephen L.

Ligand : Inhibitor Alogliptin Ligand in structure: Ligplot

References (1)

Title : Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IV - Zhang_2011_J.Med.Chem_54_510
Author(s) : Zhang Z , Wallace MB , Feng J , Stafford JA , Skene RJ , Shi L , Lee B , Aertgeerts K , Jennings A , Xu R , Kassel DB , Kaldor SW , Navre M , Webb DR , Gwaltney SL
Ref : Journal of Medicinal Chemistry , 54 :510 , 2011
Abstract :
PubMedSearch : Zhang_2011_J.Med.Chem_54_510
PubMedID: 21186796
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 3G0B Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3G0B Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3G0B Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3G0B 3D, interactive encyclopedia of proteins - PROTEOPEDIA server