Aertgeerts K

References (8)

Title : Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 - Banno_2011_Bioorg.Med.Chem_19_4953
Author(s) : Banno Y , Miyamoto Y , Sasaki M , Oi S , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Tawada M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H
Ref : Bioorganic & Medicinal Chemistry , 19 :4953 , 2011
Abstract :
PubMedSearch : Banno_2011_Bioorg.Med.Chem_19_4953
PubMedID: 21764322
Gene_locus related to this paper: human-DPP4

Title : Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554 - Maezaki_2011_Bioorg.Med.Chem_19_4482
Author(s) : Maezaki H , Banno Y , Miyamoto Y , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Sasaki M , Tsubotani S , Tani A , Funami M , Yamamoto Y , Tawada M , Aertgeerts K , Yano J , Oi S
Ref : Bioorganic & Medicinal Chemistry , 19 :4482 , 2011
Abstract :
PubMedSearch : Maezaki_2011_Bioorg.Med.Chem_19_4482
PubMedID: 21741847
Gene_locus related to this paper: human-DPP4

Title : Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125 - Miyamoto_2011_Bioorg.Med.Chem_19_172
Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H
Ref : Bioorganic & Medicinal Chemistry , 19 :172 , 2011
Abstract :
PubMedSearch : Miyamoto_2011_Bioorg.Med.Chem_19_172
PubMedID: 21163664

Title : Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IV - Zhang_2011_J.Med.Chem_54_510
Author(s) : Zhang Z , Wallace MB , Feng J , Stafford JA , Skene RJ , Shi L , Lee B , Aertgeerts K , Jennings A , Xu R , Kassel DB , Kaldor SW , Navre M , Webb DR , Gwaltney SL
Ref : Journal of Medicinal Chemistry , 54 :510 , 2011
Abstract :
PubMedSearch : Zhang_2011_J.Med.Chem_54_510
PubMedID: 21186796
Gene_locus related to this paper: human-DPP4

Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831
Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H
Ref : Journal of Medicinal Chemistry , 54 :831 , 2011
Abstract :
PubMedSearch : Miyamoto_2011_J.Med.Chem_54_831
PubMedID: 21218817
Gene_locus related to this paper: human-DPP4

Title : Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha - Aertgeerts_2005_J.Biol.Chem_280_19441
Author(s) : Aertgeerts K , Levin I , Shi L , Snell GP , Jennings A , Prasad GS , Zhang Y , Kraus ML , Salakian S , Sridhar V , Wijnands R , Tennant MG
Ref : Journal of Biological Chemistry , 280 :19441 , 2005
Abstract :
PubMedSearch : Aertgeerts_2005_J.Biol.Chem_280_19441
PubMedID: 15809306
Gene_locus related to this paper: human-FAP

Title : Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation - Aertgeerts_2004_Protein.Sci_13_412
Author(s) : Aertgeerts K , Ye S , Tennant MG , Kraus ML , Rogers J , Sang BC , Skene RJ , Webb DR , Prasad GS
Ref : Protein Science , 13 :412 , 2004
Abstract :
PubMedSearch : Aertgeerts_2004_Protein.Sci_13_412
PubMedID: 14718659
Gene_locus related to this paper: human-DPP4

Title : N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding - Aertgeerts_2004_Protein.Sci_13_145
Author(s) : Aertgeerts K , Ye S , Shi L , Prasad SG , Witmer D , Chi E , Sang BC , Wijnands RA , Webb DR , Swanson RV
Ref : Protein Science , 13 :145 , 2004
Abstract :
PubMedSearch : Aertgeerts_2004_Protein.Sci_13_145
PubMedID: 14691230